1160936-85-5

Basic information

• Product Name: (R)-2,2,2-trifluoro-1-(7-methyl-1H-indol-3-yl)-1-phenylethanol
• Synonyms: (R)-2,2,2-trifluoro-1-(7-methyl-1H-indol-3-yl)-1-phenylethanol
• CAS NO: 1160936-85-5
• Molecular Weight: 305.299
• Mol File: 1160936-85-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (R)-2,2,2-trifluoro-1-(7-methyl-1H-indol-3-yl)-1-phenylethanol(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-2,2,2-trifluoro-1-(7-methyl-1H-indol-3-yl)-1-phenylethanol(1160936-85-5)
• EPA Substance Registry System: (R)-2,2,2-trifluoro-1-(7-methyl-1H-indol-3-yl)-1-phenylethanol(1160936-85-5)

Safety Data

• Hazardous Substances Data: 1160936-85-5(Hazardous Substances Data)

Upstream product

• 933-67-5 7-methyl-1H-indole 
• 434-45-7 2,2,2-Trifluoroacetophenone 

Relevant articles and documents

High-Pressure-Mediated Asymmetric Organocatalytic Hydroxyalkylation of Indoles with Trifluoromethyl Ketones

An enantioselective hydroxyalkylation of indoles and 7-azaindole with trifluoromethyl ketones was found to be effectively promoted under high-pressure conditions with a low loading of Cinchona alkaloids (e.g., 1–3 mol% of cinchonidine). Chiral tertiary alcohols containing a trifluoromethyl group were obtained at 9 kbar with good yield and enantioselectivity up to 89%, whereas usually merely traces of products were detected at atmospheric pressure. (Figure presented.).