1160995-48-1 Usage
General Description
4-Bromopyrimidine-2-carbonitrile is a chemical compound with the molecular formula C6H3BrN2. It is a pyrimidine derivative that contains a bromine atom and a carbonitrile group. 4-Bromopyrimidine-2-carbonitrile is used in the pharmaceutical and agrochemical industries as a building block for the synthesis of various biologically active compounds, such as pharmaceutical drugs and crop protection chemicals. Its unique structure and reactivity make it an important building block for organic synthesis, and it is commonly used in research and development of new chemical compounds. 4-Bromopyrimidine-2-carbonitrile is also known for its potential laccase inhibitory activities, which makes it an interesting target for further studies in the field of enzyme inhibitors. Overall, this compound has valuable applications in the chemical and pharmaceutical industries due to its versatile reactivity and potential biological activities.
Check Digit Verification of cas no
The CAS Registry Mumber 1160995-48-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,6,0,9,9 and 5 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1160995-48:
(9*1)+(8*1)+(7*6)+(6*0)+(5*9)+(4*9)+(3*5)+(2*4)+(1*8)=171
171 % 10 = 1
So 1160995-48-1 is a valid CAS Registry Number.
1160995-48-1Relevant articles and documents
A method for preparing 2, 4 - substituted pyrimidine
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Paragraph 0010-0015, (2019/06/05)
The invention belongs to the technical field of the synthesized compounds, in particular to a 2, 4 - substituted pyrimidine of the preparation method. The method comprises the following steps: 1) the 2 - substituted pyrimidine dissolved in tetrahydrofuran, in - 60 — - 78 °C lower dropping TMP.MgCl.LiCl, dropping 1 h after adding anhydrous zinc chloride, raising the temperature to room temperature, dropping halogen, 2 h after adding hydrochloric acid solution quenching reaction; 2) reaction of the reaction solution in order to ethyl acetate extraction, drying of the organic layer concentrated, column chromatography purification to obtain the product. The invention compared with the prior art, in order to 2 - substituted pyrimidines as raw materials can be specific selection 4 substituted, at the same time does not produce 5 substituted by-product, with good selectivity, single product, is easy to be purified, with mild reaction conditions, the reaction speed and the like.
