1161078-83-6Relevant articles and documents
New pyridinone derivatives as potent HIV-1 nonnucleoside reverse transcriptase inhibitors
Le Van, Kiet,Cauvin, Christine,De Walque, Stéphane,Georges, Beno?t,Boland, Sandro,Martinelli, Valérie,Demonté, Dominique,Durant, Fran?ois,Hevesi, László,Van Lint, Carine
supporting information; experimental part, p. 3636 - 3643 (2010/04/29)
Several 5-ethyl-6-methyl-4-cycloalkyloxy-pyridin-2(1H)-ones were synthesized and evaluated for their anti HIV-1 activities against wild-type virus and clinically relevant mutant strains. A racemic mixture (10) with methyl substituents at positions 3 and 5
