116127-33-4Relevant articles and documents
STEREOSELECTIVE KINETIC PROTONATION OF CHIRAL γ-LACTONE ENOLATES
Takano, Seiichi,Kudo, Junko,Takahashi, Michiyasu,Ogasawara, Kunio
, p. 2405 - 2408 (1986)
When lithium enolates generated from five chiral α,γ-disubstituted γ-lactones are treated with proton sources, formation of the α,γ-syn epimers always predominates over the α,γ-anti epimers in ratios of 10.2-2.9:1.Higher syn/anti ratios are obtained via silyl enolates in some cases.Chirality discrimination by chiral proton source is also observed in particular cases.