116140-90-0

Basic information

• Product Name: 1,1,1-Trichloro-4-(-)-menthyloxy-3-buten-2-one
• CAS NO: 116140-90-0
• Molecular Weight: 327.679
• Mol File: 116140-90-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1,1,1-Trichloro-4-(-)-menthyloxy-3-buten-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1,1,1-Trichloro-4-(-)-menthyloxy-3-buten-2-one(116140-90-0)
• EPA Substance Registry System: 1,1,1-Trichloro-4-(-)-menthyloxy-3-buten-2-one(116140-90-0)

Safety Data

• Hazardous Substances Data: 116140-90-0(Hazardous Substances Data)

Upstream product

• 2216-51-5 (-)-menthol 
• 59938-07-7 (3E)-1,1,1-trichloro-4-ethoxybut-3-en-2-one 

Downstream Products

• 116140-95-5 Ethyl 3-(-)-menthyloxyacrylate 
• 116140-96-6 Methyl 3-(-)-menthyloxy-3-methoxypropanoate 

Relevant articles and documents

Highly Efficient Syntheses of Alkyl 3,3-Dialkoxypropanoates, Alkyl 4-Ethoxy-2-oxo-3-butenoates, and Monoprotected Malonaldehydes

Haloform reaction of 4-alkoxy-1,1,1-trichloro-3-buten-2-ones, which can be obtained by acylation of enol ethers, gives 3,3-dialkoxypropanoic esters.Transacetalization of ethyl 3,3-diethoxypropanoate with 2,2-dimethyl-1,3-propanediol, followed by reduction and oxidation with DMSO/oxalyl chloride yields a monoprotected malonaldehyde. 4-Ethoxy-2-oxo-3-butenoates are synthesized either by acylation of enol ethers with alkoxalyl chlorides or by Claisen condensation of alkyl pyruvates with orthoesters.