116146-12-4

Basic information

• Product Name: 1H-Imidazole, 1-butyl-5-phenyl-
• CAS NO: 116146-12-4
• Molecular Formula: C13H16N2
• Molecular Weight: 200.283
• Mol File: 116146-12-4.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1H-Imidazole, 1-butyl-5-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Imidazole, 1-butyl-5-phenyl-(116146-12-4)
• EPA Substance Registry System: 1H-Imidazole, 1-butyl-5-phenyl-(116146-12-4)

Safety Data

• Hazardous Substances Data: 116146-12-4(Hazardous Substances Data)

Upstream product

• 109-65-9 1-bromo-butane 
• 670-95-1 4-Phenylimidazole 
• 4316-42-1 1-Butylimidazole 
• 108-90-7 chlorobenzene 
• 71333-60-3 (E)-1-Isocyano-2-phenyl-1-tosylethene 
• 109-73-9 N-butylamine 
• 100-52-7 benzaldehyde 
• 71333-72-7 N-[(E)-2-phenyl-1-(toluene-4-sulfonyl)-vinyl]-formamide 

Relevant articles and documents

Palladium-catalyzed arylation of electron-rich heterocycles with aryl chlorides

Equation presented Palladium-catalyzed C-H activation: cheap aryl chlorides can now be used for the arylation of a wide variety of electron-rich heterocycles. The key to the success of this reaction is the use of a bulky, electron-rich phosphine ligand. No copper additives are needed.

PREPARATION OF STERICALLY MORE CROWDED 1,5-DISUBSTITUTED IMIDAZOLES BY THE REGIOSELECTIVE N-ALKYLATION

4-Substituted 1-acetylimidazoles (6), which were derived from 4(5)-substituted imidazole (1), were N-alkylated by treatment with alkyl halides.During the work-up, the resulting N-alkylated products were easily hydrolyzed into 1,5-disubstituted imidazoles (3).These reactions were regarded to be the general method for the preparation of sterically more crowded 1,5-disubstituted imidazoles (3).