116285-36-0 Usage
Description
(5ALPHA,17BETA)-N-(2-HYDROXY-1,1-DIMETHYLETHYL)-3-OXO-4-AZAANDROST-1-ENE-17-CARBOXAMIDE, also known as the M-1 metabolite of Finasteride (F342000), is a chemical compound derived from Finasteride. It functions as an inhibitor of the enzyme 5α-reductase, which is responsible for converting testosterone to the more potent androgen, 5α-dihydrotestosterone. (5ALPHA,17BETA)-N-(2-HYDROXY-1,1-DIMETHYLETHYL)-3-OXO-4-AZAANDROST-1-ENE-17-CARBOXAMIDE plays a significant role in the regulation of androgen levels in the body.
Uses
Used in Pharmaceutical Applications:
(5ALPHA,17BETA)-N-(2-HYDROXY-1,1-DIMETHYLETHYL)-3-OXO-4-AZAANDROST-1-ENE-17-CARBOXAMIDE is used as a pharmaceutical agent for the treatment of androgenetic alopecia and benign prostatic hyperplasia. Its application is based on its ability to inhibit the conversion of testosterone to 5α-dihydrotestosterone, which is a key factor in the development of these conditions.
Used in Research and Development:
In the field of research and development, (5ALPHA,17BETA)-N-(2-HYDROXY-1,1-DIMETHYLETHYL)-3-OXO-4-AZAANDROST-1-ENE-17-CARBOXAMIDE serves as a valuable compound for studying the effects of androgens on various biological processes. Its role in inhibiting 5α-reductase makes it a useful tool for understanding the mechanisms underlying androgen-related diseases and for developing new therapeutic strategies.
Used in Drug Delivery Systems:
Similar to Gallotannin, (5ALPHA,17BETA)-N-(2-HYDROXY-1,1-DIMETHYLETHYL)-3-OXO-4-AZAANDROST-1-ENE-17-CARBOXAMIDE can also be incorporated into drug delivery systems to enhance its bioavailability and therapeutic outcomes. By utilizing various organic and metallic nanoparticles as carriers, the compound can be more effectively delivered to target tissues, improving its overall efficacy in treating androgen-related conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 116285-36-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,6,2,8 and 5 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 116285-36:
(8*1)+(7*1)+(6*6)+(5*2)+(4*8)+(3*5)+(2*3)+(1*6)=120
120 % 10 = 0
So 116285-36-0 is a valid CAS Registry Number.
InChI:InChI=1/C23H36N2O3/c1-21(2,13-26)25-20(28)17-7-6-15-14-5-8-18-23(4,12-10-19(27)24-18)16(14)9-11-22(15,17)3/h10,12,14-18,26H,5-9,11,13H2,1-4H3,(H,24,27)(H,25,28)/t14-,15?,16?,17+,18?,22-,23+/m0/s1