116295-83-1

Basic information

• Product Name: coumarin-d₆
• CAS NO: 116295-83-1
• Molecular Weight: 152.098
• Mol File: 116295-83-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: coumarin-d₆(CAS DataBase Reference)
• NIST Chemistry Reference: coumarin-d₆(116295-83-1)
• EPA Substance Registry System: coumarin-d₆(116295-83-1)

Safety Data

• Hazardous Substances Data: 116295-83-1(Hazardous Substances Data)

Upstream product

• 91-64-5 coumarin 

Relevant articles and documents

Platinum on carbon-catalyzed H-D exchange reaction of aromatic nuclei due to isopropyl alcohol-mediated self- activation of platinum metal in deuterium oxide

An efficient and simple deuteration method of arenes using the platinum on carbon-isopropyl alcohol-cyclohexane-deuterium oxide combination under hydrogen gas-free conditions was accomplished. Since the hydrogen-deuterium exchange reaction cannot be promoted without isopropyl alcohol, zerovalent platinum metal (on carbon) is self-activated by the in situ-generated very low amount of hydrogen or hydrogen-deuterium gas derived from isopropyl alcohol or isopropyl alcohol-d1. Deuterium-labeled compounds with high deuterium contents can be easily isolated by the filtration of platinum on carbon and simple extraction. The present hydrogen gas-free method is safe from the viewpoint of process chemistry and various arenes possessing a variety of reducible functionalities within the molecule could be effectively and directly deuterium-labeled without undesired reduction. Copyright