116337-64-5

Basic information

• Product Name: (+-)-7-(4-Chlorobenzoyl)-2-methyl-2H-1,4-benzoxazin-3(4H)-one
• Synonyms: 3-(4-chlorobenzoyl)-9-methyl-10-oxa-7-azabicyclo[4.4.0]deca-2,4,11-trien-8-one;2H-1,4-Benzoxazin-3(4H)-one, 7-(4-chlorobenzoyl)-2-methyl-, (+-)-
• CAS NO: 116337-64-5
• Molecular Formula: C₁₆H₁₂ClNO₃
• Molecular Weight: 301.729
• Mol File: 116337-64-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (+-)-7-(4-Chlorobenzoyl)-2-methyl-2H-1,4-benzoxazin-3(4H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: (+-)-7-(4-Chlorobenzoyl)-2-methyl-2H-1,4-benzoxazin-3(4H)-one(116337-64-5)
• EPA Substance Registry System: (+-)-7-(4-Chlorobenzoyl)-2-methyl-2H-1,4-benzoxazin-3(4H)-one(116337-64-5)

Safety Data

• Hazardous Substances Data: 116337-64-5(Hazardous Substances Data)

Upstream product

• 123172-45-2 (4-Amino-3-hydroxy-phenyl)-(4-chloro-phenyl)-methanone 
• 535-11-5 Ethyl 2-bromopropionate 
• 59-49-4 2-Benzoxazolinone 
• 76751-94-5 6-(4-chlorobenzoyl)-3H-1,3-benzoxazol-2-one 
• 74-11-3 para-chlorobenzoic acid 

Relevant articles and documents

Acyl-7 dihydro-2,3 benzoxazin-1,4 ones-3 et proprietes normolipemiantes

7-Acyl-2,3-dihydro-1,4-benzoxazin-3-ones and normolipemic properties.Fibrates are still among the most widely used drugs for the treatment of dyslipoproteinemia. 7-Acyl-2,3-dihydro-1,4-benzoxazin-3-ones (Fig.1B) can be considered as conformationally restrained analogues of fibrates, such as fenofibrate.These compounds have been prepared and studied for their normolipemic activity particularly on plasma cholesterol, triglyceride and high density lipoprotein (HDL) cholesterol levels.Hepatotoxicity and mutagenicity have also been evaluated.Some of them show an interesting activity, quite comparable to fenofibrate, and are devoid of hepatotoxicity. hyperlipidemia / hypocholesterolemic drugs / fibrates / 7-acyl-1,4-benzoxazin-3-ones