116369-23-4 Usage
Description
2-Fluoro-3-trifluoromethoxy aniline is an organic compound characterized by the presence of a fluorine atom at the 2nd position and a trifluoromethoxy group at the 3rd position on the aniline molecule. It is a versatile intermediate in the synthesis of various pharmaceuticals and chemical compounds due to its unique structural features.
Uses
Used in Pharmaceutical Industry:
2-Fluoro-3-trifluoromethoxy aniline is used as a key intermediate in the synthesis of novel benzimidazoles, which are potent inhibitors of TIE-2 and VEGFR-2 tyrosine kinase receptors. These inhibitors play a crucial role in the development of targeted therapies for various diseases, including cancer.
Used in Chemical Synthesis Studies:
2-Fluoro-3-trifluoromethoxy aniline is also utilized as a coupling agent in chemical synthesis, enabling the formation of new compounds with potential applications in various fields. Its unique structural properties make it a valuable component in the development of innovative chemical entities.
Check Digit Verification of cas no
The CAS Registry Mumber 116369-23-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,6,3,6 and 9 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 116369-23:
(8*1)+(7*1)+(6*6)+(5*3)+(4*6)+(3*9)+(2*2)+(1*3)=124
124 % 10 = 4
So 116369-23-4 is a valid CAS Registry Number.
InChI:InChI=1/C7H5F4NO/c8-5-2-1-4(3-6(5)12)13-7(9,10)11/h1-3H,12H2
116369-23-4Relevant articles and documents
DISUBSTITUTED [4-(5-AMINOMETHYL-PHENYL)-PIPERIDIN-1-YL]-1H-INDOL-3-YL]-METHANONES
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Page/Page column 46-47, (2011/04/13)
The present invention extends to the compound of formula I: or a prodrug, pharmaceutically acceptable salt, or solvate of said compound. Furthermore, the present invention is directed to a pharmaceutical composition comprising a pharmaceutically effective
