116418-82-7 Usage
General Description
2,4,6(1H,3H,5H)-Pyrimidinetrione, 1,3-dicyclohexyl-5-diazo-, also known as Dicyclohexylcarbodiimide (DCC), is a chemical compound commonly used in organic synthesis. It is a white crystalline solid that is highly reactive and is known for its ability to activate carboxylic acids for amide bond formation. DCC is primarily used as a peptide coupling reagent in the synthesis of peptides and other complex organic molecules. It is important in the field of biochemistry and pharmacology, as it allows for the creation of specific peptide sequences and facilitates the development of new drugs and pharmaceuticals. Additionally, DCC is also used in the production of urethane foam and as an intermediate in the manufacturing of dyes, rubber chemicals, and pharmaceuticals.
Check Digit Verification of cas no
The CAS Registry Mumber 116418-82-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,6,4,1 and 8 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 116418-82:
(8*1)+(7*1)+(6*6)+(5*4)+(4*1)+(3*8)+(2*8)+(1*2)=117
117 % 10 = 7
So 116418-82-7 is a valid CAS Registry Number.
116418-82-7Relevant articles and documents
A 'sulfonyl-azide-free' (SAFE) aqueous-phase diazo transfer reaction for parallel and diversity-oriented synthesis
Dar'In, Dmitry,Kantin, Grigory,Krasavin, Mikhail
, p. 5239 - 5242 (2019)
Diazo transfer reactions are notoriously associated with the use of potentially explosive sulfonyl azides. The first 'sulfonyl-azide-free' (SAFE) protocol for producing diazo compounds from their active-methylene precursors via the Regitz diazo transfer reaction was developed and has displayed a remarkable substrate scope. It can be applied to generating arrays of diazo compounds for further evolution via combinatorial chemistry and a range of scaffold-generating transformations.
