116460-49-2

Basic information

• Product Name: 1-(4-methoxyphenyl)-3-phenylprop-2-yn-1-ol
• CAS NO: 116460-49-2
• Molecular Weight: 238.286
• Mol File: 116460-49-2.mol
• Article Data: 75

Chemical Properties

• CAS DataBase Reference: 1-(4-methoxyphenyl)-3-phenylprop-2-yn-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-methoxyphenyl)-3-phenylprop-2-yn-1-ol(116460-49-2)
• EPA Substance Registry System: 1-(4-methoxyphenyl)-3-phenylprop-2-yn-1-ol(116460-49-2)

Safety Data

• Hazardous Substances Data: 116460-49-2(Hazardous Substances Data)

Upstream product

• 6738-06-3 phenylethynylmagnesium bromide 
• 123-11-5 4-methoxy-benzaldehyde 
• 591-50-4 iodobenzene 
• 19115-30-1 1-(4-methoxyphenyl)-2-propyn-1-ol 
• 2170-06-1 1-Phenyl-2-(trimethylsilyl)acetylene 
• 536-74-3 phenylacetylene 
• 18402-75-0 1-triethoxysilyl-2-phenylacetylene 
• 1178514-35-6 C₁₈H₁₈O₃ 
• 28995-88-2 1-methyl-4-((phenylethynyl)sulfonyl)benzene 
• 932-88-7 1-iodo-2-phenylethyne 
• 105-13-5 4-Methoxybenzyl alcohol 
• 1407998-87-1 2-(1-(4-methoxyphenyl)-3-phenylprop-2-yn-1-yl)isoindoline-1,3-dione 
• 67-56-1 methanol 
• 4440-01-1 lithium phenylacetylide 

Downstream Products

• 1168152-76-8 ethyl 5-benzyl-4-(4-methoxyphenyl)-2-methyl-1-phenyl-1H-pyrrole-3-carboxylate 
• 1266366-00-0 2,3-diiodo-1-(4-methoxyphenyl)-1H-indene 
• 1266366-43-1 3-bromo-2-iodo-1-(4-methoxyphenyl)-1H-indene 
• 1183859-93-9 dimethyl 5-methoxy-1-oxo-3-phenyl-1H-inden-2-ylphosphonate 
• 1407998-87-1 2-(1-(4-methoxyphenyl)-3-phenylprop-2-yn-1-yl)isoindoline-1,3-dione 
• 1422391-30-7 (E)-1-bromo-4-(3-(4-methoxyphenyl)-5-phenylpent-1-en-4-ynyl)benzene 
• 1422391-31-8 (E)-4-(3-(4-methoxyphenyl)-5-phenylpent-1-en-4-ynyl)phenyl acetate 
• 1422391-32-9 1-methoxy-4-(1,1,5-triphenylpent-1-en-4-yn-3-yl)benzene 
• 1422391-29-4 (E)-1-(3,5-diphenylpent-1-en-4-yn-3-yl)-4-methoxybenzene 
• 1618678-09-3 1-(4-chlorophenyl)-2-methyl-3-acetyl-4-(4-methoxyphenyl)-5-benzyl-1H-pyrrole 
• 1310025-05-8 5-(1-(4-methoxyphenyl)-3-phenylprop-2-ynyl)-1-methylindolin-2-one 
• 1300119-78-1 2-(4-chlorobenzyl)-3-(4-methoxyphenyl)-5-phenyl-4-pentyn-1-ol 
• 1300119-82-7 2-(4-chlorobenzyl)-3-(4-methoxyphenyl)-5-phenyl-4-pentyn-1-ol 

Relevant articles and documents

Visible Light-Induced Reductive Alkynylation of Aldehydes by Umpolung Approach

Reductive alkynylation of aldehydes by the Umpolung approach was developed using a photoredox catalyst under blue LED irradiation. Ketyl radicals, generated by single-electron reduction of aldehydes through proton-coupled electron transfer (PCET), reacted with electrophilic alkynylsulfones. Sterically demanding bulky aldehydes reacted smoothly under the Umpolung reaction conditions. Moreover, the alkynylation proceeded chemoselectively with an aryl aldehyde group in the presence of other carbonyl groups including an aliphatic aldehyde group.

Straightforward Stereoselective Synthesis of Seven-Membered Oxa-Bridged Rings through in Situ Generated Cycloheptenol Derivatives

An iodine-mediated stereoselective synthesis of seven-membered oxa-bridged rings via in situ generated cycloheptenols was reported. This process was realized through the combination of C-C σ-bond cleavage and C-O bond-forming reactions in a one-pot fashion from simple and easily accessible raw materials. The formation of carbon radicals initiated by I2 was the key to the reaction.

Gold-Catalyzed Regioselective Synthesis of Pyrazolo[1,4]oxazepines via Intramolecular 7-endo-dig Cyclization

An efficient gold-catalyzed intramolecular regioselective synthesis of pyrazolo[1,4]oxazepines were developed from alkynyl-substituted pyrazoles via 7-endo dig cyclization. In this reaction a new C–N bond was formed and substituted pyrazolo[1,4]oxazepines