116486-80-7Relevant articles and documents
Addition Reactions of F-Alkyl Iodides to Carbon-Carbon Double Bonds Promoted by Metallic Tin(0)-Metal Salt System
Kuroboshi, Manabu,Ishihara, Takashi
, p. 299 - 304 (1988)
F-Alkyl iodides readily reacted with a variety of alkenes in methanol at room temperature under the influence of metallic tin(0)-silver(I) acetate or metallic tin(0)-copper(I) chloride to afford the corresponding addition products, F-alkylated iodides, in
Visible light promoted fluoroalkylation of alkenes and alkynes using 2-bromophenol as a catalyst
Zhu, Erlin,Liu, Xiao-Xiao,Wang, An-Jun,Mao, Ting,Zhao, Liang,Zhang, Xingang,He, Chun-Yang
, p. 12259 - 12262 (2019)
We report a new protocol for the fluoroalkylation of alkenes and alkynes by using 2-bromophenol as a catalyst. This reaction can be tailored for different reaction modes by altering the base and solvent, which feature a wide substrate scope and excellent functional group tolerance with high chemo- and regioselectivities. We further propose a mechanism involving an electron donor-acceptor (EDA) complex.
Diethylzinc-Mediated Radical 1,2-Addition of Alkenes and Alkynes
Li, Xin,He, Songtao,Song, Qiuling
supporting information, p. 2994 - 2999 (2021/05/04)
A novel diethylzinc-mediated radical 1,2-addition of perfluoroalkyl iodides to unactivated alkenes and alkynes is presented, which demonstrates a novel way to generate an ethyl difluoroacetate radical. This method is highly efficient and gives full conversions of the substrates, high yields of the products, and negligible byproducts and requires no column chromatography purifications. The mild conditions enable this protocol to exhibit excellent functional group compatibility.
Metal-Free Activation of C-I Bonds and Perfluoroalkylation of Alkenes with Visible Light Using Phosphine Catalysts
Helmecke, Lucas,Spittler, Michael,Baumgarten, Kai,Czekelius, Constantin
supporting information, p. 7823 - 7827 (2019/10/11)
An efficient metal-free, photomediated iodo perfluoroalkylation under mild conditions was developed. Using catalytic amounts (10 mol %) of phosphines and blue light irradiation, various olefins are transformed into the corresponding addition products with