116498-58-9Relevant articles and documents
Lignan and neolignan glycosides from stems of Alangium premnifolium
Yuasa, Kaori,Ide, Toshinori,Otsuka, Hideaki,Ogimi, Choei,Hirata, Eiji,Takushi, Anki,Takeda, Yoshio
, p. 611 - 615 (1997)
From a methanol extract of stems of Alangium premnifolium, eight lignan derivatives were isolated. Structural elucidation by a spectroscopic method revealed that four of them were new lignan or neolignan glycosides.
Lignan Glycosides from the Twigs of Chaenomeles sinensis and Their Biological Activities
Kim, Chung Sub,Subedi, Lalita,Kim, Sun Yeou,Choi, Sang Un,Kim, Ki Hyun,Lee, Kang Ro
supporting information, p. 1174 - 1178 (2015/06/02)
Phytochemical investigation of the twigs of Chaenomeles sinensis led to the isolation and identification of six new lignan glycosides, chaenomiside A-F (1-6), along with five known ones (7-11). Their chemical structures were determined by spectroscopic methods, including NMR, MS, ECD, and GC/MS analyses. All the isolated compounds (1-11) were tested for their inhibitory effects on nitric oxide (NO) production in lipopolysaccharide-activated murine microglial cells and the secretion of nerve growth factor (NGF) in a C6 rat glioma cell line. Compound 6 significantly reduced NO levels in the murine microglia BV2 cells with an IC50 value of 21.3 μM, and compounds 1, 3, and 6 were potent stimulants of NGF release with stimulation levels of 151.74 ± 6.77%, 144.31 ± 7.49%, and 167.61 ± 18.5%, respectively.
Two new lignan xylosides from the barks of Prunus ssiori and Prunus padus
Yoshinari,Sashida,Shimomura
, p. 3301 - 3303 (2007/10/02)
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