116527-73-2

Basic information

• Product Name: 1,1-diethoxy-3,3-(diethoxycarbonyl)-6-benzyloxyhexan
• Synonyms: 1,1-diethoxy-3,3-(diethoxycarbonyl)-6-benzyloxyhexan
• CAS NO: 116527-73-2
• Molecular Weight: 424.535
• Mol File: 116527-73-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1,1-diethoxy-3,3-(diethoxycarbonyl)-6-benzyloxyhexan(CAS DataBase Reference)
• NIST Chemistry Reference: 1,1-diethoxy-3,3-(diethoxycarbonyl)-6-benzyloxyhexan(116527-73-2)
• EPA Substance Registry System: 1,1-diethoxy-3,3-(diethoxycarbonyl)-6-benzyloxyhexan(116527-73-2)

Safety Data

• Hazardous Substances Data: 116527-73-2(Hazardous Substances Data)

Upstream product

• 105-53-3 diethyl malonate 
• 2032-35-1 Bromoacetaldehyde diethyl acetal 
• 21339-47-9 diethyl 2-(2,2-diethoxyethyl)malonate 
• 26420-79-1 1-chloro-3-benzyloxypropane 

Downstream Products

• 116527-75-4 2-(3-benzyloxypropyl)-3-oxo-2,3,5,6,11,11b-hexahydro-1H-indolizino<8,7-b>indol-2-carbonsaure-ethylester 

Relevant articles and documents

EINE NEUE SYNTHESE VON VINBLASTIN-DERIVATEN III. SYNTHESE UND REAKTIONEN VON 21,Nb-SECO-CLEAVAMIN-DERIVATEN ALS VORLAUFER ZU 20'-DEETHYL-20'-DEOXYVINBLASTIN UND (+/-)-16α-METHOXYCARBONYL-20-DEETHYL-15,20-DIHYDROCLEAVAMIN

In a new concept for the synthesis of 20'-deethyl-20'deoxyvinblastine, Nb-seco-cleavamine derivatives 1a,2a are possible precursors.For the synthesis of these compounds the indolizino indoles 8I,II were treated with benzyl chloroformate/aq. sodium