116632-58-7

Basic information

• Product Name: 8-BROMOQUINOLIN-5-AMINE
• Synonyms: 8-BROMOQUINOLIN-5-AMINE;5-Amino-8-bromoquinoline;5-Quinolinamine, 8-bromo-
• CAS NO: 116632-58-7
• Molecular Formula: C₉H₇BrN₂
• Molecular Weight: 223.1
• Mol File: 116632-58-7.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 353.3 °C at 760 mmHg
• Flash Point: 167.5 °C
• Appearance: /
• Density: 1.649 g/cm³
• Vapor Pressure: 3.61E-05mmHg at 25°C
• Refractive Index: 1.732
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 2.90±0.29(Predicted)
• CAS DataBase Reference: 8-BROMOQUINOLIN-5-AMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 8-BROMOQUINOLIN-5-AMINE(116632-58-7)
• EPA Substance Registry System: 8-BROMOQUINOLIN-5-AMINE(116632-58-7)

Safety Data

• Hazardous Substances Data: 116632-58-7(Hazardous Substances Data)

Usage

General Description

8-Bromoquinolin-5-amine is a chemical compound with the molecular formula C9H7BrN2. It is a derivative of quinoline and is commonly used as a building block in organic synthesis. 8-BROMOQUINOLIN-5-AMINE is often used in the pharmaceutical industry for the production of various drugs and active pharmaceutical ingredients. It is also used in research and development of new chemical compounds. 8-Bromoquinolin-5-amine has potential applications in the development of novel therapeutics and may have antimicrobial properties. It is important for its role in the synthesis of various pharmaceuticals and related compounds.

InChI:InChI=1/C9H7BrN2/c10-7-3-4-8(11)6-2-1-5-12-9(6)7/h1-5H,11H2

Upstream product

• 139366-35-1 8-bromo-5-nitroquinoline 
• 20377-01-9 5-quinolyl azide 
• 7439-89-6 iron 
• 16567-18-3 8-bromoquinoline 
• 7647-01-0 hydrogenchloride 

Downstream Products

• 1452182-88-5 N-(1-(8-aminoquinolin-5-yl)-3-methyl-1H-pyrazol-5-yl)-4-tert-butyl-3-fluorobenzenesulfonamide 
• 1452183-67-3 N-(1-(8-bromoquinolin-5-yl)-3-methyl-1H-pyrazol-5-yl)-4-tert-butyl-3-fluorobenzenesulfonamide 
• 855877-61-1 acetic acid-[4-(5-amino-quinoline-8-sulfonyl)-anilide] 

Relevant articles and documents

Hetaroyl cyclohexanedione derivatives with herbicidal effect

Hetaroyl derivatives of the formula I where: R1and R2are each hydrogen, nitro, halogen, cyano, thiocyanato, hydroxyl, mercapto, C1-C6-alkyl, C1-C6-alkoxy, C1-C6-alkylthio, C1-C6-alkylsulfinyl, C1-C6-alkylsulfonyl or C1-C6-alkoxysulfonyl, where the last 6 radicals may be substituted and/or functionalized; phenyl, phenoxy, phenylthio, phenylsulfinyl or phenylsulfonyl, where the last 5 radicals may be substituted; Z is an unsubstituted or substituted four-membered unsaturated, partially or fully saturated chain consisting of three carbons and one nitrogen; Q is unsubstituted or substituted cyclohexane-1,3-dione linked at position 2; and their agriculturally useful salts. A process for preparing the hetaroyl derivatives, compositions comprising them, and the use of these derivatives or these compositions comprising them for controlling undesirable plants.

PHOTOLYSIS OF PYRIDYL, QUINOLYL, AND ISOQUINOLYL AZIDES IN HYDROHALOGENOIC ACIDS

Photolysis of 4-azido-pyridine and -quinoline in hydrohalogenoic acids gave the 3-amino-4-halogeno compounds (2) via azirine or azacycloheptatetraene intermediates, whereas their N-oxides (4), under similar conditions, gave the 4-amino-3-halogeno compounds (5) presumably via nitrenium ion intermediates.In the 3-azidoquinoline and 4-azidoisoquinoline series, both free bases (6a, 8a) and N-oxides (6b, 8b) gave similar results to 4-azidopyridine and -quinoline N-oxides (4).