1166399-01-4Relevant articles and documents
On the inhibition of HIV-1 protease by hydrazino-ureas displaying the N→C{double bond, long}O interaction
Waibel, Michael,Pitrat, Delphine,Hasserodt, Jens
experimental part, p. 3671 - 3679 (2009/09/27)
To create novel HIV-1 protease (HIV PR) inhibitors, we have extended our investigations of the N→C{double bond, long}O interaction as a moiety that reproduces electrostatic properties of the transition state of peptidolysis. Consequently, we prepared a se