116757-23-4

Basic information

• Product Name: 3-[(4-methoxyphenyl)sulfanyl]-2-phenylindole
• Synonyms: 3-[(4-methoxyphenyl)sulfanyl]-2-phenylindole
• CAS NO: 116757-23-4
• Molecular Weight: 331.438
• Mol File: 116757-23-4.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: 3-[(4-methoxyphenyl)sulfanyl]-2-phenylindole(CAS DataBase Reference)
• NIST Chemistry Reference: 3-[(4-methoxyphenyl)sulfanyl]-2-phenylindole(116757-23-4)
• EPA Substance Registry System: 3-[(4-methoxyphenyl)sulfanyl]-2-phenylindole(116757-23-4)

Safety Data

• Hazardous Substances Data: 116757-23-4(Hazardous Substances Data)

Upstream product

• 948-65-2 2-phenyl-indole 
• 5335-87-5 4,4'-dimethoxyphenyl disulfide 
• 696-63-9 4-Methoxybenzenethiol 
• 54006-72-3 3-bromo-2-phenyl-1H-indole 
• 13141-38-3 2-phenylethynylaniline 
• 1950-68-1 4-methoxybenzenesulfonyl hydrazide 
• 199277-23-1 1-azido-2-(phenylethynyl)benzene 
• 5720-07-0 4-methoxyphenylboronic acid 

Relevant articles and documents

B(C6F5)3-Catalyzed Electron Donor-Acceptor Complex-Mediated Aerobic Sulfenylation of Indoles under Visible-Light Conditions

An efficient B(C6F5)3-catalyzed aerobic oxidative C-S cross-coupling reaction of thiophenol with indoles was developed, affording a wide range of diaryl sulfides in good yields. An electron donor-acceptor complex between B(C6F5)3 and indoles was formed, facilitating the photoinduced single-electron transfer (SET) from indole substrates to the B(C6F5)3 catalyst. This protocol demonstrates a new reaction model using B(C6F5)3 as a single-electron oxidant.

Microwave assisted metal-/oxidant-free cascade electrophilic sulfenylation/5-endo-dig cyclization of 2-alkynylanilines to generate diversified 3-sulfenylindoles

A metal-/oxidant-free sustainable protocol for the synthesis of 3-sulfenylindoles based on electrophilic cyclization of 2-alkynylanilines has been developed under microwave irradiation. Herein, catalytic amount of iodine and stoichiometric amount of sulfonyl hydrazides were employed as catalyst and electrophiles respectively to induce the 5-endo-dig cyclization of 2-alkynylanilines. This strategy allows a wide substrate scope, demonstrates good functional group tolerance, utilizes easily available reagents and overcome multistep synthesis.

Metal-free synthesis of 3-sulfenylindoles via an iodine-mediated electrophilic cyclisation of 2-alkynylanilines with disulfides

An efficient and metal-free method was developed to synthesise 3-sulfenylindoles via the iodine-mediated electrophilic cyclisation of 2-alkynylanilines with disulfides. In the presence of I2, various 3-sulfenylindoles were obtained in moderate