1167571-21-2Relevant articles and documents
3-(3-Aryloxyaryl)imidazo[1,2-a]pyridine sulfones as liver X receptor agonists
Singhaus, Robert R.,Bernotas, Ronald C.,Steffan, Robert,Matelan, Edward,Quinet, Elaine,Nambi, Ponnal,Feingold, Irene,Huselton, Christine,Wilhelmsson, Anna,Goos-Nilsson, Annika,Wrobel, Jay
scheme or table, p. 521 - 525 (2010/04/26)
Replacement of a quinoline with an imidazo[1,2-a]pyridine in a series of liver X receptor (LXR) agonists incorporating a [3-(sulfonyl)aryloxyphenyl] side chain provided high affinity LXR ligands 7. In functional assays of LXR activity, good agonist potency and efficacy were found for several analogs.