116817-79-9

Basic information

• Product Name: phenyl N-methyl-3-(1-naphthalenyloxy)-3-(2-thienyl)-propylcarbamate
• Synonyms: phenyl N-methyl-3-(1-naphthalenyloxy)-3-(2-thienyl)-propylcarbamate
• CAS NO: 116817-79-9
• Molecular Weight: 417.529
• Mol File: 116817-79-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: phenyl N-methyl-3-(1-naphthalenyloxy)-3-(2-thienyl)-propylcarbamate(CAS DataBase Reference)
• NIST Chemistry Reference: phenyl N-methyl-3-(1-naphthalenyloxy)-3-(2-thienyl)-propylcarbamate(116817-79-9)
• EPA Substance Registry System: phenyl N-methyl-3-(1-naphthalenyloxy)-3-(2-thienyl)-propylcarbamate(116817-79-9)

Safety Data

• Hazardous Substances Data: 116817-79-9(Hazardous Substances Data)

Upstream product

• 321-38-0 1-Fluoronaphthalene 
• 13636-02-7 3-(N,N-dimethylamino)-1-(thien-2-yl)propan-1-ol 
• 88-15-3 2-Acetylthiophene 
• 1885-14-9 phenyl chloroformate 
• 116817-11-9 N,N-dimethylamino-3-(1-naphthanyloxy)-3-(2-thienyl)-1-propanamine 

Downstream Products

• 116817-13-1 duloxetine 

Relevant articles and documents

METHOD FOR PRODUCING DULOXETINE HYDROCHLORIDE

PROBLEM TO BE SOLVED: To provide a new method for producing (S)-(+)-N-methyl-3-(1-naphthyloxy)-3-(2-thienyl)propylamine hydrochloride (general name: duloxetine hydrochloride) useful as an antidepressant. SOLUTION: In a method for producing duloxetine hydrochloride, a solution obtained by dissolving a crude product containing duloxetine hydrochloride in a dissolving solvent (a first dissolution step) and acetone are mixed (a mixing step), the duloxetine hydrochloride precipitated in the obtained mixed solution is temporarily dissolved (a second dissolution step), and then the duloxetine hydrochloride is precipitated. SELECTED DRAWING: None COPYRIGHT: (C)2017,JPOandINPIT