116849-45-7

Basic information

• Product Name: N-carbamate
• Synonyms: N-carbamate
• CAS NO: 116849-45-7
• Molecular Weight: 252.227
• Mol File: 116849-45-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-carbamate(CAS DataBase Reference)
• NIST Chemistry Reference: N-carbamate(116849-45-7)
• EPA Substance Registry System: N-carbamate(116849-45-7)

Safety Data

• Hazardous Substances Data: 116849-45-7(Hazardous Substances Data)

Upstream product

• 22509-74-6 N-ethoxycarbonylphthalimide 

Downstream Products

• 524-38-9 N-hydroxyphthalimide 

Relevant articles and documents

Kinetic Evidence for the Occurrence of a Stepwise Mechanism in the Aminolysis of N-Ethoxycarbonylphthalimide

The nucleophilic second-order rate constants for the reactions of N-ethoxycarbonylphthalimide (ECPH) with morpholine, piperazine, 1,4-diazabicyclooctane, and ethylenediamine exhibit a Bronsted plot of slope (βnuc) 1.2 +/-0.3.The significantly high value of βnuc reveals that the expulsion of the living group from a zwitterionic tetrahedral addition intermediate is the rate-determining step.The reactivity of hydroxylamine is nearly 105-fold larger than that expected from the Bronsted plot of slope (βnuc) 1.2.The hydroxyaminolysis of ECPH reveals general base catalysis.The results obtained on the hydroxyaminolysis of ECPH in the presence of external general base, acetate, reveal that the rate-determining step changes as the buffer concentration is increased and, consequently, it provides evidence for the existence of an intermediate on the reaction co-ordinate.The rate constants for the reactions of monoprotonated 1,4-diazabicyclooctane and piperazine show positive deviations from the Bronsted plot.