116849-51-5Relevant articles and documents
Synthesis of O-arylxanthates esters and derivatives
Humeres,Debacher,De Souza
, p. 1071 - 1079 (2008/09/18)
No successful attempts have been made to synthesize O-arylxanthate esters from metal salts with alkylating agents because the metal derivatives are too unstable for the effective synthesis of the esters. In this work, substituted R-phenylxanthates (R = H, p-MeO, o-Me, p-F) were obtained as barium salts that upon reaction with alkyl halides produced O-arylxanthate esters. The ethylaminolysis of methyl O-phenylxanthate formed diethyl thiourea as the final product because of the similar nucleofugality of phenoxy and ethylthioxy moieties. A new method was used to obtain N-ethyl O-p-methoxyphenyl- thioncarbamate from the reaction of p-methoxyphenol and N-ethylisothiocyanate in a heterogeneous mixture of dichloromethane and aqueous phosphate buffer, pH 7.
