116887-93-5

Basic information

• Product Name: Butanamide, N-hydroxy-4-(methylthio)-2-[(triphenylmethyl)amino]-, (2S)-
• CAS NO: 116887-93-5
• Molecular Formula: C24H26N2O2S
• Mol File: 116887-93-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Butanamide, N-hydroxy-4-(methylthio)-2-[(triphenylmethyl)amino]-, (2S)-(CAS DataBase Reference)
• NIST Chemistry Reference: Butanamide, N-hydroxy-4-(methylthio)-2-[(triphenylmethyl)amino]-, (2S)-(116887-93-5)
• EPA Substance Registry System: Butanamide, N-hydroxy-4-(methylthio)-2-[(triphenylmethyl)amino]-, (2S)-(116887-93-5)

Safety Data

• Hazardous Substances Data: 116887-93-5(Hazardous Substances Data)

Upstream product

• 22737-36-6 O-Trimethylsilylhydroxylamine 
• 93984-97-5 N-Trityl-L-Methionin-(1-hydroxybenzotriazolylester) 

Downstream Products

• 116864-51-8 (S)-2-Methyl-4-tritylamino-1,2-oxazinan-3-on 
• 116864-50-7 (S)-1-Methoxy-3-(N-tritylamino)-2-pyrrolidon 
• 116947-11-6 (S)-4-(N-Tritylamino)-1,2-oxazinan-3-on 
• 116887-94-6 (S)-1-Hydroxy-3-(N-tritylamino)-2-pyrrolidinon 
• 116864-48-3 [3-Hydroxycarbamoyl-3-(trityl-amino)-propyl]-dimethyl-sulfonium; iodide 
• 116887-95-7 N-Trityl-L-methionin-N'-methylhydroxylamid 
• 128669-48-7 C₄₀H₄₄N₂O₂SSi 

Relevant articles and documents

Application of N-Tritylmethionine in the Preparation of Heterocycles of Biological and Synthetic Interest

Treatment of the methylsulfonium salts of the corresponding N-tritylmethionine derivatives with sodium hydride or potassium tert-butoxide provides the heterocycles N-trityl-L-homoserine lactone (3), (S)- and (R)-3-(N-tritylamino)tetrahydrofuran (7a, 7b), (S)-1-hydroxy-3-(N-tritylamino)-2-pyrrolidinone (14), (S)-4-(N-tritylamino)-1,2-oxazinan-3-one (15), (S)-3-(N-tritylamino)-2-pyrrolidone (23), (S)-1-tert-butyloxycarbonylamino-3-(N-tritylamino)-2-pyrrolidone (27), and (S)-2-methyl-4-(N-tritylamino)-1,2-oxazinan-3-one (18).Methylation of 14 and 15 yields (S)-1-methoxy-3-(N-tritylamino)-2-pyrrolidone (17) and 18, respectively.The stereochemistry of compounds 3, 7a, and 17 has been determined by X-ray crystal structure analysis.