116987-46-3

Basic information

• Product Name: -2 methyl-2 thiazolidine carboxylate d'ethyle-4 (R)
• CAS NO: 116987-46-3
• Molecular Weight: 273.397
• Mol File: 116987-46-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: -2 methyl-2 thiazolidine carboxylate d'ethyle-4 (R)(CAS DataBase Reference)
• NIST Chemistry Reference: -2 methyl-2 thiazolidine carboxylate d'ethyle-4 (R)(116987-46-3)
• EPA Substance Registry System: -2 methyl-2 thiazolidine carboxylate d'ethyle-4 (R)(116987-46-3)

Safety Data

• Hazardous Substances Data: 116987-46-3(Hazardous Substances Data)

Upstream product

• 1123-27-9 1-(1-hydroxycyclohexyl)ethan-1-one 
• 868-59-7 L-cysteine ethyl ester hydrochloride 

Relevant articles and documents

Synthese et etude structurale de derives substitues en -2 du thiazolidine carboxylate d'ethyle-4 (R)

Pharmacological properties of thiazolidine derivatives are of great interest.For this purpose we prepared two series: 2-hydroxyalkyl-4-carbethoxythiazolidines and 2-carbalkoxyalkyl-4-carbethoxythiazolidines.Their syntheses involve a condensation reaction between L-carbethoxycystein and several α-hydroxyketones or β-ketoesters.Compound 4 and 5 was obtained as an unequal mixture of diastereoisomers.Protons nmr spectra at 300 MHz in the presence of trifluoroacetic acid shows a modification of diastereoisomer percentages which indicate the existence of an equilibrium through an imminium ion intermediate.Therefore, the stereoselectivity observed reflects the relative stability of the different diastereoisomers.