1171113-86-2Relevant articles and documents
Preparation of 5-substituted 2-(2-alkyl/aryl-1H-imidazol-4-yl)oxazoles and 5-substituted 2-(2-alkyl/arylthiazol-4-yl)oxazoles by utilizing 5-substituted 2-(2-bromo-1,1-diethoxyethyl)oxazole as a synthon
St. Laurent, Denis R.,Romine, Jeffrey L.
experimental part, p. 1445 - 1458 (2009/12/09)
Synthetic access to oxazolyl-substituted heterocycles including oxazolylimidazoles, -thiazoles, and -oxazoles is gained from a masked α-halo ketone attached to the 2-position of the oxazole ring. 3-Bromo-2,2-diethoxy-N-(2-oxoalkyl)propionamides readily cy