117112-62-6

Basic information

• Product Name: (2R,3R)-cis-1,3-O-benzylidene-1,2,3-octadec-4-enetriol
• Synonyms: (2R,3R)-cis-1,3-O-benzylidene-1,2,3-octadec-4-enetriol
• CAS NO: 117112-62-6
• Molecular Weight: 388.591
• Mol File: 117112-62-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (2R,3R)-cis-1,3-O-benzylidene-1,2,3-octadec-4-enetriol(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,3R)-cis-1,3-O-benzylidene-1,2,3-octadec-4-enetriol(117112-62-6)
• EPA Substance Registry System: (2R,3R)-cis-1,3-O-benzylidene-1,2,3-octadec-4-enetriol(117112-62-6)

Safety Data

• Hazardous Substances Data: 117112-62-6(Hazardous Substances Data)

Upstream product

• 25791-20-2 (n-tetradecyl)triphenylphosphonium bromide 
• 99274-32-5 2,4-O-benzylidene-D-threose 
• 3006-41-5 4,6-O-benzylidene-α,β-D-galactopyranose 
• 1125-88-8 benzaldehyde dimethyl acetal 
• 100-52-7 benzaldehyde 

Downstream Products

• 117112-63-7 (2S,3R,4E)-2-amino-1,3-benzylidene-4-octadecene-1,3-diol 
• 114275-40-0 (2R,3R)-trans-2-azide-1,3-O-benzylidene-1,3-octadec-4-enediol 
• 124313-98-0 (2R,3R,4E)-1,3-benzylidene-2-methanesulfonyl-4-octadecene-1,2,3-triol 
• 117112-64-8 (2S,3R)-N-palmitoyl-1,3-O-benzylidene-4,5-dihydro-D-sphingosine 
• 117112-65-9 (2S,3R)-3-O-benzoyl-4,5-dihydro-1-deoxyceramide-1-bromide 
• 34324-89-5 (2S,3R,4E)-1-(β-D-galactopyranosyloxy)-2-(hexadecanoylamino)-3-hydroxyoctadec-4-ene 
• 117112-66-0 (2S,3R)-3-O-benzoyl-4,5-dihydro-1-deoxyceramide-1-sulfonic acid 
• 143517-08-2 1-OTBDPS ceramide 
• 143517-09-3 Benzoic acid (E)-(R)-1-[(S)-2-(tert-butyl-diphenyl-silanyloxy)-1-hexadecanoylamino-ethyl]-hexadec-2-enyl ester 
• 94069-99-5 (2S,3R)-N-palmitoyl-3-O-benzoyl-1-O-(2',3',4',6'-tetra-O-acetyl-β-D-galactopyranosyl)-D-sphingosine 
• 116447-99-5 (2S,3R,4E)-1,3-benzylidene-2-(hexadecanoylamido)-4-octadecene-1,3-diol 
• 124314-02-9 (2S,3R)-2-amino-1,3-O-benzylidene-1,3-octadecanediol 
• 124314-01-8 (2S,3R)-2-azide-1,3-O-benzylidene-1,3-octadecanediol 
• 124314-00-7 (2S,3R)-1,3-O-benzylidene-2-O-methanesulfonyl-1,2,3-octadecanetriol 

Relevant articles and documents

4,5-Cis Unsaturated α-GalCer Analogues Distinctly Lead to CD1d-Mediated Th1-Biased NKT Cell Responses

The total synthesis of 4,5-cis unsaturated α-GalCer analogues was achieved, and their immune-response altering activity was assessed in vitro as well as in vivo in mice. Using glycosyl iodide as a glycosyl donor, construction of the sphingosine unit was shortened by four steps and single α-stereoselectivity was achieved in good yield (67%). With regard to the therapeutic use of α-GalCer, the novel analogues (1b and 1c) distinctly induced a Th1-biased cytokine response, avoiding induction of a contradictory response and overstimulation.

SYNTHESIS OF D-ERYTHRO-1-DEOXYDIHYDROCERAMIDE-1-SULFONIC ACID

New D-erythro-1-deoxydihydroceramide-1-sulfonic acid, isolated from alkali-stable lipids in a non-photosynthetic marine diatom Nitzschia alba, was synthesized from galactose as a chiral precursor using the Hanessian-Hullar reaction as the key step in the