117241-61-9 Usage
Description
Tetracenomycin D3 is a tetracenomycin derivative characterized by the presence of four hydroxy substituents at positions 3, 8, 10, and 12 on its 1-methyl-6,11-dioxo-6,11-dihydrotetracene-2-carboxylic acid structure. This unique chemical composition endows tetracenomycin D3 with potential applications in various fields.
Uses
Used in Pharmaceutical Industry:
Tetracenomycin D3 is used as a pharmaceutical compound for its potential therapeutic properties. Its unique structure allows it to interact with specific biological targets, making it a promising candidate for the development of new drugs.
Used in Research and Development:
In the field of research and development, tetracenomycin D3 serves as a valuable tool for studying the interactions between small molecules and biological systems. Its chemical properties can be exploited to investigate various biological processes and pathways, contributing to a better understanding of disease mechanisms and the development of targeted therapies.
Used in Drug Delivery Systems:
Similar to gallotannin, tetracenomycin D3 can be incorporated into drug delivery systems to enhance its bioavailability and therapeutic efficacy. By employing various carriers such as organic and metallic nanoparticles, the limitations of tetracenomycin D3 can be overcome, leading to improved delivery and treatment outcomes.
Used in Chemical Synthesis:
Tetracenomycin D3's unique structure also makes it a valuable starting material for the synthesis of novel compounds with potential applications in various industries, including pharmaceuticals, agrochemicals, and materials science. Its chemical properties can be further modified to create new molecules with enhanced properties and functionalities.
Check Digit Verification of cas no
The CAS Registry Mumber 117241-61-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,7,2,4 and 1 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 117241-61:
(8*1)+(7*1)+(6*7)+(5*2)+(4*4)+(3*1)+(2*6)+(1*1)=99
99 % 10 = 9
So 117241-61-9 is a valid CAS Registry Number.
InChI:InChI=1/C20H12O8/c1-6-13-7(3-11(22)14(6)20(27)28)2-9-16(18(13)25)19(26)15-10(17(9)24)4-8(21)5-12(15)23/h2-5,21-23,25H,1H3,(H,27,28)
117241-61-9Relevant articles and documents
Cloning, sequencing, and heterologous expression of the elmGHIJ genes involved in the biosynthesis of the polyketide antibiotic elloramycin from Streptomyces olivaceus Tue2353
Rafanan Jr., Elpidio R.,Le, Linda,Zhao, Lili,Decker, Heinrich,Shen, Ben
, p. 444 - 449 (2007/10/03)
Elloramycin A (1) belongs to a small family of naphthacenequinones characterized by a unique highly hydroxylated cyclohexenone moiety. A cosmid clone 16F4, harboring genes for the production of 1 from Streptomyces olivaceus Tue2353, has been previously isolated. DNA sequence analysis of a 3.2-kb fragment from 16F4 revealed four open reading frames - the elmGHIJ genes. Heterologous expressions of the elmGHI genes in either Escherichia coli or Streptomyces lividans, followed by biochemical characterizations of the ElmGHI proteins, established ElmG as tetracenomycin B2 oxygenase, ElmH as tetracenomycin F1 monooxygenase, and ElmI as tetracenomycin F2 cyclase. These results provide direct biochemical evidence for the hypothesis that the biosynthesis of 1 in S. olivaceus parallels that of tetracenomycin C (2) in Streptomyces glaucescens and support the notion that the biosynthesis of the highly hydroxylated cyclohexenone moiety in other polyketides most likely follows the same paradigm as the tetracenomycin B2 or A2 oxygenase.
