117379-48-3

Basic information

• Product Name: 4-(1-phenylsulphonylpyrrol-3-yl)-4-oxobut-2-enoic acid
• CAS NO: 117379-48-3
• Molecular Weight: 305.311
• Mol File: 117379-48-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-(1-phenylsulphonylpyrrol-3-yl)-4-oxobut-2-enoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(1-phenylsulphonylpyrrol-3-yl)-4-oxobut-2-enoic acid(117379-48-3)
• EPA Substance Registry System: 4-(1-phenylsulphonylpyrrol-3-yl)-4-oxobut-2-enoic acid(117379-48-3)

Safety Data

• Hazardous Substances Data: 117379-48-3(Hazardous Substances Data)

Upstream product

• 108-31-6 maleic anhydride 
• 16851-82-4 N-phenylsulfonylpyrrole 

Relevant articles and documents

Gastric anti-secretory, anti-ulcer and cytoprotective properties of substituted (E)-4-phenyl- and heteroaryl-4-oxo-2-butenoic acids

A class of anti-secretory, anti-ulcer and cytoprotective agents, the substituted (E)-4-phenyl and heteroaryl-4-oxo-2-butenoic acids, is described.This chemical structure is not related to those of any known anti-cholinergic drugs, histamine H2-receptor antagonists or prostaglandins.Five compounds, 4-(2-methoxyphenyl)- 15, 4-(4-methoxyphenyl)- 22, 4-(3,4-dimethoxyphenyl)- 32, 4-(3,4,5-trimethoxyphenyl)- 40, and 4-(2-furanyl)-4-oxo-2-butenoic acid 44, have cytoprotective activity at a very low dose (0.6 mg/kg, p.o.) and anti-secretory and anti-ulcer activities at higher doses.One of these compounds, RU 38086 40, has been selected for clinical evaluation.Keywords - anti-ulcer agents / cytoprotective agents / (E)-4-phenyl- and heteroaryl-4-oxo-2-butenoic acids.