117379-73-4

Basic information

• Product Name: 2-Hydroxy-4-(2-hydroxy-4-methoxy-phenyl)-4-oxo-butyric acid
• Synonyms: 2-Hydroxy-4-(2-hydroxy-4-methoxy-phenyl)-4-oxo-butyric acid
• CAS NO: 117379-73-4
• Molecular Weight: 240.213
• Mol File: 117379-73-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-Hydroxy-4-(2-hydroxy-4-methoxy-phenyl)-4-oxo-butyric acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Hydroxy-4-(2-hydroxy-4-methoxy-phenyl)-4-oxo-butyric acid(117379-73-4)
• EPA Substance Registry System: 2-Hydroxy-4-(2-hydroxy-4-methoxy-phenyl)-4-oxo-butyric acid(117379-73-4)

Safety Data

• Hazardous Substances Data: 117379-73-4(Hazardous Substances Data)

Upstream product

• 552-41-0 1-(2-hydroxy-4-methoxyphenyl)ethanone 
• 563-96-2 2,2-dihydroxyacetic acid 

Downstream Products

• 86691-00-1 (E)-4-(2-hydroxy-4-methoxyphenyl)-4-oxo-2-butenoic acid 

Relevant articles and documents

Gastric anti-secretory, anti-ulcer and cytoprotective properties of substituted (E)-4-phenyl- and heteroaryl-4-oxo-2-butenoic acids

A class of anti-secretory, anti-ulcer and cytoprotective agents, the substituted (E)-4-phenyl and heteroaryl-4-oxo-2-butenoic acids, is described.This chemical structure is not related to those of any known anti-cholinergic drugs, histamine H2-receptor antagonists or prostaglandins.Five compounds, 4-(2-methoxyphenyl)- 15, 4-(4-methoxyphenyl)- 22, 4-(3,4-dimethoxyphenyl)- 32, 4-(3,4,5-trimethoxyphenyl)- 40, and 4-(2-furanyl)-4-oxo-2-butenoic acid 44, have cytoprotective activity at a very low dose (0.6 mg/kg, p.o.) and anti-secretory and anti-ulcer activities at higher doses.One of these compounds, RU 38086 40, has been selected for clinical evaluation.Keywords - anti-ulcer agents / cytoprotective agents / (E)-4-phenyl- and heteroaryl-4-oxo-2-butenoic acids.