1174372-99-6

Basic information

• Product Name: (4-chlorophenyl)[2-(2-hydroxy-5-methoxyphenyl)-3,3-dimethylindolin-1-yl]methanone
• Synonyms: (4-chlorophenyl)[2-(2-hydroxy-5-methoxyphenyl)-3,3-dimethylindolin-1-yl]methanone
• CAS NO: 1174372-99-6
• Molecular Weight: 407.897
• Mol File: 1174372-99-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (4-chlorophenyl)[2-(2-hydroxy-5-methoxyphenyl)-3,3-dimethylindolin-1-yl]methanone(CAS DataBase Reference)
• NIST Chemistry Reference: (4-chlorophenyl)[2-(2-hydroxy-5-methoxyphenyl)-3,3-dimethylindolin-1-yl]methanone(1174372-99-6)
• EPA Substance Registry System: (4-chlorophenyl)[2-(2-hydroxy-5-methoxyphenyl)-3,3-dimethylindolin-1-yl]methanone(1174372-99-6)

Safety Data

• Hazardous Substances Data: 1174372-99-6(Hazardous Substances Data)

Upstream product

• 51459-50-8 (4-chlorophenyl)(2-hydroxy-3,3-dimethyl-2,3-dihydroindol-1-yl)methanone 
• 150-76-5 4-methoxy-phenol 

Relevant articles and documents

Role of 2-naphthyl ether intermediate in formation of isolable atropisomers derived from the coupling reaction of (2-hydroxy-3,3-dimethylindolin-l-yl)-(substituted phenyl)methanones with 2-naphthol

The formation pathway of the atropisomers derived from the reaction of (2-hydroxy-3,3-dimethylindolin-l-yl)(4-substituted phenyl)methanones with 2-naphthol in the presence of BF3·Et2O was discussed on the basis of the isolation of the 2-naphthyl ether intermediate whose structure was determined by single crystal X-ray analysis. The results indicate that the coupling reaction proceeds through stepwise mechanism, i.e., the ether intermediate formation followed by Fries-type rearrangement.