1174752-17-0Relevant articles and documents
Synthesis and characterization of various 5′-dye-labeled ribonucleosides
De Schutter, Coralie,Roy, Vincent,Favetta, Patrick,Pavageau, Corentin,Maisonneuve, Stéphane,Bogliotti, Nicolas,Xie, Juan,Agrofoglio, Luigi A.
, p. 6552 - 6563 (2018)
Hitherto unknown chromophoric nucleosides are reported. This novel set of visibly coloured dye-labeled 5′-nucleosides, including 1,2,4,5-tetrazine, dicyanomethylene-4H-pyran, benzophenoxazinone, 9,10-anthraquinone and azobenzene chromophores, were prepared mainly under Cu-catalyzed azide-alkyne cycloaddition (CuAAC). The design criteria are outlined. Several derivatives possess in supplement a fluorescence property. The absorption and fluorescence spectra of all coloured nucleosides were recorded to study their potential as visible-range probes. Such nucleodyes are of great interest for future competitive lateral flow test MIP-based strips.