1174929-50-0

Basic information

• Product Name: 4-[2-(2-chloro-5-fluoro-benzyl)-1-phenyl-1H-indole-3-carbonyl]-piperazine-1-carboxylic acid tert-butyl ester
• Synonyms: 4-[2-(2-chloro-5-fluoro-benzyl)-1-phenyl-1H-indole-3-carbonyl]-piperazine-1-carboxylic acid tert-butyl ester
• CAS NO: 1174929-50-0
• Molecular Weight: 548.057
• Mol File: 1174929-50-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-[2-(2-chloro-5-fluoro-benzyl)-1-phenyl-1H-indole-3-carbonyl]-piperazine-1-carboxylic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[2-(2-chloro-5-fluoro-benzyl)-1-phenyl-1H-indole-3-carbonyl]-piperazine-1-carboxylic acid tert-butyl ester(1174929-50-0)
• EPA Substance Registry System: 4-[2-(2-chloro-5-fluoro-benzyl)-1-phenyl-1H-indole-3-carbonyl]-piperazine-1-carboxylic acid tert-butyl ester(1174929-50-0)

Safety Data

• Hazardous Substances Data: 1174929-50-0(Hazardous Substances Data)

Upstream product

• 1174929-06-6 4-(2-chloro-1-phenyl-1H-indole-3-carbonyl)-piperazine-1-carboxylic acid tert-butyl ester 
• 81778-09-8 1-(bromomethyl)-2-chloro-5-fluorobenzene 

Relevant articles and documents

CYCLIC INDOLE-3-CARBOXAMIDES, THEIR PREPARATION AND THEIR USE AS PHARMACEUTICALS

The present invention relates to cyclic indole-3-carboxamides of the Formula (I), wherein A, R, R10, R20, R30, R40, n, p and q have the meanings indicated in the claims, which are valuable pharmaceutical active compounds. Specifically, they inhibit the enzyme renin and modulate the activity of the renin-angiotensin system, and are useful for the treatment of diseases such as hypertension, for example. The invention furthermore relates to processes for the preparation of the compounds of the Formula (I), their use and pharmaceutical compositions comprising them.