1174988-10-3

Basic information

• Product Name: C₁₇H₂₃N₃O
• Synonyms: C₁₇H₂₃N₃O
• CAS NO: 1174988-10-3
• Molecular Weight: 285.389
• Mol File: 1174988-10-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₇H₂₃N₃O(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₇H₂₃N₃O(1174988-10-3)
• EPA Substance Registry System: C₁₇H₂₃N₃O(1174988-10-3)

Safety Data

• Hazardous Substances Data: 1174988-10-3(Hazardous Substances Data)

Upstream product

• 1681-36-3 4-chloro-3-methylpyridine 
• 51387-92-9 4-amino-2-((diethylamino)methyl)phenol 

Relevant articles and documents

Design, synthesis and structure-activity relationships of (1H-pyridin-4-ylidene)amines as potential antimalarials

(1H-Pyridin-4-ylidene)amines containing lipophilic side chains at the imine nitrogen atom were prepared as potential clopidol isosteres in the development of antimalarials. Their antiplasmodial activity was evaluated in vitro against the Plasmodium falciparum W2 (chloroquine-resistant) and FCR3 (atovaquone-resistant) strains. The most active of these derivatives, 4m, had an IC50 of 1 μM against W2 and 3 μM against FCR3. Molecular modeling studies suggest that (1H-pyridin-4-ylidene)amines may bind to the ubiquinol oxidation Qo site of cytochrome bc1.