117527-51-2Relevant articles and documents
Synthesis of congeners and prodrugs. 3. Water-soluble prodrugs of taxol with potent antitumor activity
Deutsch,Glinski,Hernandez,Haugwitz,Narayanan,Suffness,Zalkow
, p. 788 - 792 (1989)
Taxol has shown good in vivo antitumor activity in a number of test systems. The formulation of taxol for antitumor testing has been difficult. Esterification at either C-2' or C-7 resulted in loss of in vitro tubulin assembly activity but not cytotoxicit
Paclitaxel weakly acidic derivative active medicine carrier liposome and preparation method and application thereof
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Paragraph 0043-0045; 0047, (2020/05/01)
The invention belongs to the field of liposome drug delivery, and relates to a paclitaxel weakly acidic derivative active medicine carrier liposome and a preparation method and application thereof. The paclitaxel weakly acidic derivative is provided, and
Taxane drug and doxorubicin prodrug self-assembled nanoparticles and application thereof
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Paragraph 0031; 0068-0070, (2020/12/30)
The invention belongs to the field of new auxiliary materials and new dosage forms of pharmaceutical preparations, relates to taxane drug and doxorubicin prodrug self-assembled nanoparticles and application thereof, and in particular relates to synthesis