117535-03-2

Basic information

• Product Name: 6-chloro-3-cyano-2-phenylfuro<3,2-c>pyridine
• CAS NO: 117535-03-2
• Molecular Weight: 254.675
• Mol File: 117535-03-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 6-chloro-3-cyano-2-phenylfuro<3,2-c>pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 6-chloro-3-cyano-2-phenylfuro<3,2-c>pyridine(117535-03-2)
• EPA Substance Registry System: 6-chloro-3-cyano-2-phenylfuro<3,2-c>pyridine(117535-03-2)

Safety Data

• Hazardous Substances Data: 117535-03-2(Hazardous Substances Data)

Upstream product

• 14432-16-7 2-chloro-4-nitropyridine-N-oxide 
• 13602-59-0 2,4-dichloropyridine-N-oxide 
• 935-02-4 3-Phenyl-2-propynonitrile 

Relevant articles and documents

THE REACTION OF 4-CHLOROPYRIDINE 1-OXIDES WITH ACTIVATED ACETYLENES. A CONVENIENT ONE-STEP SYNTHESIS OF FUROPYRIDINES

The reaction of 4-chloro- and 4-pseudohalogeno-pyridine 1-oxides with activated acetylenes (phenylcyanoacetylene, methyl phenylpropiolate, phenylpropiolaldehyde, methyl propiolate, and ethynyl p-tolyl sulphone) gave good yields of substituted furopyridines 7.With 1-phenyl-2-methanesulphonylacetylene under mild conditions the initial -shift product 9 was isolated and converted to 7 with base.The structure of 7 was established unambiguously by using Eu(fod)3-induced NMR shifts.The mechanism of the reaction is discussed briefly and consecutive -shifts are proposed to account for the formation 7.