117554-09-3

Basic information

• Product Name: (2R)-2-(benzylamino)butane-1,4-diol
• Synonyms: (2R)-2-(benzylamino)butane-1,4-diol
• CAS NO: 117554-09-3
• Molecular Weight: 195.261
• Mol File: 117554-09-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (2R)-2-(benzylamino)butane-1,4-diol(CAS DataBase Reference)
• NIST Chemistry Reference: (2R)-2-(benzylamino)butane-1,4-diol(117554-09-3)
• EPA Substance Registry System: (2R)-2-(benzylamino)butane-1,4-diol(117554-09-3)

Safety Data

• Hazardous Substances Data: 117554-09-3(Hazardous Substances Data)

Upstream product

• 100-46-9 benzylamine 
• 117554-02-6 (4R,5R)-4-(N-benzylamino)-5-((1'R,2'S,5'R)-menthyloxy)-butyrolactone 

Relevant articles and documents

ASYMMETRIC 1,4-ADDITIONS TO 5-ALKOXY-2(5H)-FURANONES ENANTIOSELECTIVE SYNTHESIS AND ABSOLUTE CONFIGURATION DETERMINATION OF β-AMINO-γ-BUTYROLACTONES AND AMINO DIOLS

The synthesis of enantiomerically pure β-amino-γ-butyrolactones via asymmetric conjugate addition of various amines to 5-methyloxy-2(5H)-furanone is described.This route provides access to new multifunctional homochiral building blocks.The absolute configuration of the β-amino-γ-butyrolactones is established by X-ray analysis and 1H NMR correlation.The conjugate addition of amines to 2(5H)-furanone, 5-alkyl-2(5H)-furanones and 5-alkoxy-2(5H)-furanones was studied and an enhanced reactivity was observed in 2(5H)-furanones due to a γ-alkoxy-effect.The synthetic utility of the asymmetric amine addition is illustrated in an efficient route to various optically pure 2-amino-1,4-butanediols.