117686-69-8Relevant articles and documents
Durenesulfonic Acid Derivatives as New Condensing Reagents in the Nucleotide Synthesis Following the Triester Method
Losse, Guenter,Stang, Norbert
, p. 19 - 24 (2007/10/02)
As shown by the synthesis of a series of ribonucleotide blocks durenesulfonyl chloride/1-methylimidazole and 1-(3-durenylsulfonyloxy)-6-nitrobenzotriazole (15) are adventageous alternative condensing reagents for the triester method.Hereby the 2'-OH function of the ribose is protected by the 4-methoxybenzyl group, which can be removed suitably by dry TFA/anisole instead of trityl tetrafluoroborate.