117758-87-9Relevant articles and documents
Phosphonated Fluoroquinolones, Antibacterial Analogs Thereof, and Methods for the Prevention and Treatment of Bone and Joint Infections
-
, (2008/12/09)
The present invention relates to phosphonated fluoroquinolones, antibacterial analogs thereof, and methods of using such compounds. These compounds are useful as antibiotics for prevention and/or the treatment of bone and joint infections, especially for the prevention and/or treatment of osteomyelitis.
N-Glycosyl phosphonamidates: Potential transition-state analogue inhibitors of glycopeptidases
Ferro, Vito,Weiler, Larry,Withers, Stephen G.,Ziltener, Herman
, p. 313 - 318 (2007/10/03)
The synthesis of N-glycosyl phosphonamidates has been accomplished via the coupling of peracetylated glycosylamines with an appropriate phosphonochloridate in the presence of pyridine. The resulting glycosyl phosphonamidate esters are dealkylated with bro