118001-74-4

Basic information

• Product Name: 4-(1,3-THIAZOL-4-YLMETHOXY)BENZALDEHYDE
• Synonyms: 4-(1,3-THIAZOL-4-YLMETHOXY)BENZALDEHYDE;Benzaldehyde, 4-(4-thiazolylmethoxy)-
• CAS NO: 118001-74-4
• Molecular Formula: C₁₁H₉NO₂S
• Molecular Weight: 219.26
• Mol File: 118001-74-4.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 4-(1,3-THIAZOL-4-YLMETHOXY)BENZALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(1,3-THIAZOL-4-YLMETHOXY)BENZALDEHYDE(118001-74-4)
• EPA Substance Registry System: 4-(1,3-THIAZOL-4-YLMETHOXY)BENZALDEHYDE(118001-74-4)

Safety Data

• Hazardous Substances Data: 118001-74-4(Hazardous Substances Data)

Upstream product

• 3364-76-9 4-chloromethylthiazole 
• 123-08-0 4-hydroxy-benzaldehyde 
• 7709-58-2 4-(chloromethyl)thiazole hydrochloride 

Relevant articles and documents

Iminoxycarboxylates and derivatives as inhibitors of leukotriene biosynthesis

The present invention relates to a compound of formula or a pharmaceutically acceptable salt thereof wherein W is optionally substituted aryl or heteroaryl; X is a valence bond, or methylene, divalent alkylene, alkenylene, alkynylene or alkyloxy; Q is a valence bond, or --O--, --S--, >NR4 or >NCOR5 ; Y is optionally substituted phenyl, biphenyl, naphthyl, tetrahydronaphthyl, indolyl, pyridyl, or benzo b!thienyl, thienyl, thiazolyl, or thiazolylphenyl; R1 is alkyl, cycloalkyl, alkoxyalkyl, aryl or arylalkyl, heteroaryl or heteroarylalkyl; R2 is hydrogen, alkyl or hydroxyalkyl; A is a valence bond or is selected from alkylene, alkenylene, alkynylene, cycloalkylene, phenylene, pyridylene, thienylene and furylene; and M is a pharmaceutically acceptable, metabolically cleavable group, --OR6, --NR6 R7, --NH-tetrazoyl, --NH-2-, 3-, or 4-pyridyl, and --NH-2-, 4-, or 5-thiazolyl which inhibit leukotriene biosynthesis and are useful in the treatment of inflammatory disease states. Also disclosed are leukotriene biosynthesis inhibiting compositions and a method for inhibiting lipoxygenase activity and leukotriene biosynthesis.