118026-15-6

Basic information

• Product Name: N,N,6-trimethyl-2-(4-methylphenyl)imidazo[1,2-a]pyridin-3-ylchloroacetamide hydrochloride
• Synonyms: N,N,6-trimethyl-2-(4-methylphenyl)imidazo[1,2-a]pyridin-3-ylchloroacetamide hydrochloride
• CAS NO: 118026-15-6
• Molecular Weight: 378.301
• Mol File: 118026-15-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N,N,6-trimethyl-2-(4-methylphenyl)imidazo[1,2-a]pyridin-3-ylchloroacetamide hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: N,N,6-trimethyl-2-(4-methylphenyl)imidazo[1,2-a]pyridin-3-ylchloroacetamide hydrochloride(118026-15-6)
• EPA Substance Registry System: N,N,6-trimethyl-2-(4-methylphenyl)imidazo[1,2-a]pyridin-3-ylchloroacetamide hydrochloride(118026-15-6)

Safety Data

• Hazardous Substances Data: 118026-15-6(Hazardous Substances Data)

Upstream product

• 118026-14-5 N,N,6-trimethyl-2-(4-methylphenyl)-imidazo[1,2-α]pyridine-3-α-hydroxyacetamide 

Relevant articles and documents

Preparation method of zolpidem

The invention discloses a preparation method of a zolpidem intermediate. In the process of preparing the zolpidem intermediate N, N, 6-trimethyl-2-(4-methylphenyl)-imidazo [1, 2-alpha] pyridine-3-acetamide hydrochloride by reducing N, N, 6-trimethyl-2-(4-methylphenyl)-imidazo [1, 2-alpha] pyridine-3-acetamide hydrochloride, through process optimization and parameter adjustment, by using a 10% palladium-carbon catalyst and combining the reaction condition of hydrogen pressure of 0.02-0.09 MPa, the conversion effect of the N, N, 6-trimethyl-2-(4-methylphenyl)-imidazo [1, 2-alpha] pyridine-3-chloroacetamide hydrochloride is promoted, side reactions and impurities are reduced, the product yield is increased, the problem of low product synthesis yield in the process of preparing N, N, 6-trimethyl-2-(4-methylphenyl)-imidazo [1, 2-alpha] pyridine-3-acetamide hydrochloride through reduction reaction in zolpidem production is solved, and the production cost of zolpidem tartrate is reduced.