118058-68-7

Basic information

• Product Name: 4-(acetylamino)phenoxymethyl ethyl carnonate
• CAS NO: 118058-68-7
• Molecular Weight: 253.255
• Mol File: 118058-68-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-(acetylamino)phenoxymethyl ethyl carnonate(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(acetylamino)phenoxymethyl ethyl carnonate(118058-68-7)
• EPA Substance Registry System: 4-(acetylamino)phenoxymethyl ethyl carnonate(118058-68-7)

Safety Data

• Hazardous Substances Data: 118058-68-7(Hazardous Substances Data)

Upstream product

• 35179-98-7 chloromethyl ethyl carbonate 
• 103-90-2 4-acetaminophenol 
• 82619-14-5 ethoxycarbonyloxymethyl iodide 

Relevant articles and documents

Overcoming steric effects in the coupling reaction of alkyloxycarbonyloxymethyl (AOCOM) halides with phenols: an efficient synthesis of AOCOM phenolic prodrugs

Steric hindrance is a key factor in the coupling reaction of AOCOM halides with phenols. Sterically unhindered alkoxy groups favor the formation of acylated phenol. Under phase-transfer conditions, alkylated phenol is favored regardless of steric hindrance.