1180670-65-8

Basic information

• Product Name: 1-(4'-bromophenyl)-4,4,4-trifluoro-1-butanone
• Synonyms: 1-(4'-bromophenyl)-4,4,4-trifluoro-1-butanone
• CAS NO: 1180670-65-8
• Molecular Weight: 281.072
• Mol File: 1180670-65-8.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: 1-(4'-bromophenyl)-4,4,4-trifluoro-1-butanone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4'-bromophenyl)-4,4,4-trifluoro-1-butanone(1180670-65-8)
• EPA Substance Registry System: 1-(4'-bromophenyl)-4,4,4-trifluoro-1-butanone(1180670-65-8)

Safety Data

• Hazardous Substances Data: 1180670-65-8(Hazardous Substances Data)

Upstream product

• 22731-70-0 1-(4-bromophenyl)prop-2-en-1-one 
• 99-90-1 para-bromoacetophenone 
• 1350637-18-1 (4-bromophenyl)(2,2-difluorocyclopropyl)methanone 
• 692-51-3 (E)-trimethyl(3,3,3-trifluoroprop-1-en-1-yl)silane 
• 1122-91-4 4-bromo-benzaldehyde 
• 887144-97-0 Togni's reagent 
• 109240-30-4 1-(4-bromophenyl)cyclopropan-1-ol 
• 2314-97-8 iodotrifluoromethane 
• 85020-75-3 1-(4-bromophenyl)-2-propyn-1-ol 
• 2039-82-9 1-bromo-4-ethenyl-benzene 
• 353-83-3 1,1,1-trifluoro-2-iodoethane 
• 28131-17-1 2-(4-bromophenyl)acrylic acid 
• 41841-16-1 (4-bromo-phenyl)-acetic acid methyl ester 
• 342808-62-2 1-(4-bromophenyl)vinyl acetate 

Downstream Products

• 1488363-78-5 (S)-3-{4-[1-(4'-tert-butyl-2,6-dimethylbiphenyl-4-yloxy)-4,4,4-trifluorobutyl]benzamido}propanoic acid 

Relevant articles and documents

Synthesis of β-CF 3 Ketones through Copper/Silver Cocatalyzed Oxidative Coupling of Enol Acetates with ICH 2 CF 3

A simple method for the synthesis of β-CF 3 ketones through copper/silver cocatalyzed oxidative coupling of enol acetates with ICH 2 CF 3 has been developed. Enol acetates were chosen as the source of carbonyl group, giving the β-CF 3 ketones in moderate yields. Control experiments imply that a radical process maybe involved in this reaction.

Base-Promoted Double-Bond-Migration/Hydrolysis/Isomerization of 4-Aryl-1,1,1-trifluorobut-2-en-2-yl Trifluoromethanesulfonates: A Metal-Free Approach to β-Trifluoromethyl Ketones

A method for the synthesis of β-trifluoromethyl ketones promoted by a base is described. In the presence of DBU, 1-aryl-4,4,4-trifluoromethylbutanones with various functional groups were obtained through the reaction of 4-aryl-1,1,1-trifluorobut-2-en-2-yl

Copper/Silver Cocatalyzed Oxidative Coupling of Vinylarenes with ICH2CF3 or ICH2CHF2 Leading to β-CF3/CHF2-Substituted Ketones

A novel copper/silver cocatalyzed oxidative coupling of vinylarenes with ICH2CF3 or ICH2CHF2 through a radical process has been developed. The transformation provides an attractive approach to β-CF3/CHF2-substituted ketones, with the advantages of easily available starting materials and operational simplicity.