118198-70-2

Basic information

• Product Name: 1,2-Benzenediol, 4-(1-hydroxyoctyl)-
• CAS NO: 118198-70-2
• Molecular Formula: C14H22O3
• Molecular Weight: 238.327
• Mol File: 118198-70-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1,2-Benzenediol, 4-(1-hydroxyoctyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-Benzenediol, 4-(1-hydroxyoctyl)-(118198-70-2)
• EPA Substance Registry System: 1,2-Benzenediol, 4-(1-hydroxyoctyl)-(118198-70-2)

Safety Data

• Hazardous Substances Data: 118198-70-2(Hazardous Substances Data)

Usage

Derivative of

Resorcinol
A dihydroxy benzene compound from which 1,2-Benzenediol, 4-(1-hydroxyoctyl)is derived.

Structural feature

Long hydrocarbon chain attached to one of the hydroxyl groups
A characteristic of the compound's structure, which differentiates it from its parent compound, resorcinol.

Applications

Cosmetics and personal care products
Used as a skin conditioning agent and antioxidant in the industry.

Potential applications

Pharmaceuticals, corrosion inhibitor in industrial processes

Research status

Further research needed
Indicates that the compound's properties and potential uses are not yet fully understood and require additional study.

Upstream product

• 13125-66-1 n-heptylmagnesium bromide 
• 139-85-5 3,4-dihydroxybenzaldehyde 

Downstream Products

• 7580-46-3 4-n-Octylcatechol 

Relevant articles and documents

Quantitative structure-activity relationship of catechol derivatives inhibiting 5-lipoxygenase

Various catechol derivatives (β-substituted 3,4-dihydroxystyrenes, 1-substituted 3,4-dihydroxybenzenes, and 6-substituted 2,3-dihydroxynaphthalenes) were synthesized and their inhibition of 5-lipoxygenase was assayed. Their structure-activity relationships were examined quantitatively with substituent and structural parameters and regression analysis. The variations in the inhibitory activity were explained in bilinear hydrophobic parameter (log P) terms, and steric (molecular thickness) and electronic (proton nuclear magnetic resonance (1H-NMR) chemical shift of the proton adjacent to the catechol group) parameter terms. The hydrophobicity of the inhibitor molecule was important, and the optimum value of log P was about 4.3-4.6, beyond which inhibition did not increase further. A low electron density of the aromatic ring containing the catechol group and the greater thickness of the lipophilic side chains were unfavorable to the activity. The results added a physicochemical basis for the selection of candidate compounds for developmental studies.