118249-07-3 Usage
Description
1-(2-(3-iodo-4-aminophenyl)ethyl)-4-(3-(trifluoromethyl)phenyl)piperazine is a complex chemical compound featuring a piperazine ring with various functional groups, including an aminophenyl, ethyl, iodine, trifluoromethyl, and phenyl groups. 1-(2-(3-iodo-4-aminophenyl)ethyl)-4-(3-(trifluoromethyl)phenyl)piperazine holds potential pharmaceutical significance due to its structural resemblance to selective serotonin reuptake inhibitors (SSRIs) and serotonin receptor antagonists.
Uses
Used in Pharmaceutical Applications:
1-(2-(3-iodo-4-aminophenyl)ethyl)-4-(3-(trifluoromethyl)phenyl)piperazine is used as a potential candidate for the development of new pharmaceuticals, particularly in the realm of central nervous system (CNS) drugs. Its structural similarity to SSRIs and serotonin receptor antagonists suggests that it may have applications in treating conditions related to serotonin dysregulation, such as depression and anxiety.
Used in Radiolabeling Studies:
In the field of medical imaging and diagnostics, 1-(2-(3-iodo-4-aminophenyl)ethyl)-4-(3-(trifluoromethyl)phenyl)piperazine is used as a compound for radiolabeling. The presence of iodine in its structure makes it suitable for attachment to radioactive isotopes, which can then be used to track biological processes or diagnose conditions within the body.
Further Research:
1-(2-(3-iodo-4-aminophenyl)ethyl)-4-(3-(trifluoromethyl)phenyl)piperazine is used as a subject of ongoing research to fully understand its properties and potential applications. Further studies are necessary to explore its pharmacological profile, safety, and efficacy in various therapeutic areas.
Check Digit Verification of cas no
The CAS Registry Mumber 118249-07-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,8,2,4 and 9 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 118249-07:
(8*1)+(7*1)+(6*8)+(5*2)+(4*4)+(3*9)+(2*0)+(1*7)=123
123 % 10 = 3
So 118249-07-3 is a valid CAS Registry Number.
InChI:InChI=1/C19H21F3IN3/c20-19(21,22)15-2-1-3-16(13-15)26-10-8-25(9-11-26)7-6-14-4-5-18(24)17(23)12-14/h1-5,12-13H,6-11,24H2
118249-07-3Relevant articles and documents
Preparation and biodistribution of -[125I]Iodo-4-aminophenyl)ethyl]-4-[3-(trifluoromethyl)phenyl]piperazine and -[125I]Iodo-4-azidophenyl)ethyl]-4-[3-(trifluoromethyl)phenyl]piperazine
Chumpradit,Kung,Billings,Guo,Wu,Shih
, p. 543 - 547 (2007/10/02)
The iodinated analogue of 1-[2-(4-aminophenyl)ethyl]-4-[3-(trifluoromethyl)phenyl]piperazine (PAPP), IPAPP (4), and the corresponding azido compound azido-IPAPP (5) were synthesized. The corresponding no-carrier-added 125I (T( 1/2 ) = 60 days, 35-60 keV) labeled compounds were also prepared. High specific binding was observed from in vitro binding studies using rat brain tissue preparation; K(i) = 20 and 17.5 nM against [3H]-5-HT. In vivo biodistribution studies in rats showed that azido-[125I]IPAPP passed through intact blood-brain barrier and localized in the brain. Ex vivo autoradiography of rat brain sections exhibited a diffuse uptake pattern, which may be due to specific and nonspecific binding. The results indicate that IPAPP and azido-IPAPP may not be suitable to image the serotonin receptor in the brain.
