118249-11-9Relevant articles and documents
High-affinity disaccharide binding by tricyclic synthetic lectins
Sookcharoenpinyo, Bunyarithi,Klein, Emmanuel,Ferrand, Yann,Walker, D. Barney,Brotherhood, Peter R.,Ke, Chenfeng,Crump, Matthew P.,Davis, Anthony P.
supporting information; experimental part, p. 4586 - 4590 (2012/06/30)
Stay flexible: Rigid preorganization is not always the best approach to molecular recognition. Unlike previous synthetic lectins, new receptors (see picture) were synthesized that possess conformational freedom which allows hydrophobically driven collapse
Phenol-containing macrocyclic diamides as new catalysts in the highly regioselective conversion of epoxides to β-hydroxy thiocyanates
Sharghi,Nasseri,Niknam
, p. 7287 - 7293 (2007/10/03)
The regioselective ring-opening reactions of some epoxides with ammonium thiocyanate in the presence of a series of new phenol-containing macrocyclic diamides and also dibenzo-18-crown-6-, 18-crown-6-, benzo-15-crown-5-, and pyridine-containing macrocyclic diamide have been studied. The epoxides were subject to cleavage by NH4SCN in the presence of these catalysts under mild reaction conditions in various aprotic solvents. In this study, reagents and conditions have been discovered with which the individual β-hydroxy thiocyanates can be synthesized in high yield and with more than 90% regioselectivity. The results can be discussed in terms of a four-step mechanism: (1) formation of complex between catalyst and NH4SCN, (2) release of SCN- nucleophile from the complex, (3) reaction of the active nucleophile at the less sterically hindered site in the epoxide, and (4) regeneration of catalyst. The major advantages of this method are as follows: (1) high regioselectivity, (2) simple regeneration of catalyst, (3) its reuse through several cycles without a decrease in activity, and (4) ease of workup of the reaction.
SYNTHETIC MACROCYCLIC LIGANDS. VI. LITHIUM ION-SELECTIVE FLUORESCENT EMISSION WITH CROWNED BENZO- AND NAPHTO-THIAZOLYLPHENOLS
Tanigawa, Isamu,Tsuemoto, Kiyoka,Kaneda, Takahiro,Misumi, Soichi
, p. 5327 - 5330 (2007/10/02)
Synthesis of fluorescent crowned benzo- and naphto-thiazolylphenols are described and lithium ion-selective fluorescent emission is observed under the restricted conditions.