118306-76-6 Usage
Description
5-(2-Chloroethyl)Oxindole is an organic compound with the molecular formula C10H10ClNO. It is a derivative of oxindole, featuring a chloroethyl group at the 5th position. 5-(2-Chloroethyl)Oxindole is known for its potential applications in the pharmaceutical industry due to its unique structural properties.
Uses
Used in Pharmaceutical Industry:
5-(2-Chloroethyl)Oxindole is used as a key intermediate in the synthesis of various pharmaceutical compounds. Its unique structure allows for the development of new drugs with specific therapeutic properties.
Used in Synthesis of Antidepressant and Antipsychotic Drugs:
5-(2-Chloroethyl)Oxindole is used as a building block for the synthesis of piperazinyl-heterocyclic compounds, such as Ziprasidone (Z485000). These compounds are utilized in the treatment of bipolar disorders and associated symptoms, providing relief and improving the quality of life for patients suffering from these conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 118306-76-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,8,3,0 and 6 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 118306-76:
(8*1)+(7*1)+(6*8)+(5*3)+(4*0)+(3*6)+(2*7)+(1*6)=116
116 % 10 = 6
So 118306-76-6 is a valid CAS Registry Number.
118306-76-6Relevant articles and documents
CONJUGATES OF AMPK INHIBITORS AND PROTAC DEGRADERS AND RELATED USES
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Paragraph 0333; 0350, (2022/01/12)
The present disclosure relates to compounds of Formula (I): T-L-D, stereoisomers thereof, prodrugs thereof, and pharmaceutically acceptable salts thereof, wherein T is an AMPK inhibiting moiety; L is a linking moiety; and D is a PROTAC degrading moiety. The present disclosure also relates to uses of the compounds, e.g., to inhibit AMP-Activated protein kinase (AMPK), degrading AMPK protein, and/or treat cancer in a subject.
AMP-ACTIVATED PROTEIN KINASE INHIBITORS AND METHODS OF MAKING AND USING THE SAME
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Page/Page column 72, (2021/01/23)
The present disclosure relates to compounds of Formula (I): (I); stereoisomers thereof, prodrugs thereof, and pharmaceutically acceptable salts thereof. The present disclosure also relates to uses of the compounds, e.g., to inhibit AMP-Activated protein kinase (AMPK) and treat cancer in a subject.
HETEROCYCLIC COMPOUNDS, PROCESS FOR PREPARATION OF THE SAME AND USE THEREOF
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Paragraph 0376; 0379; 0380, (2017/07/15)
The present invention provides a heterocyclic compound represented by the formula (I), its stereoisomers, or a pharmaceutically acceptable salt thereof, pharmaceutical compositions thereof, and their use in preparing a medicament for the prevention and/or treatment of central nervous system disease.
