118353-47-2

Basic information

• Product Name: (+)-(S)-benzoin Z-oxime
• Synonyms: (+)-(S)-benzoin Z-oxime
• CAS NO: 118353-47-2
• Molecular Weight: 227.263
• Mol File: 118353-47-2.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (+)-(S)-benzoin Z-oxime(CAS DataBase Reference)
• NIST Chemistry Reference: (+)-(S)-benzoin Z-oxime(118353-47-2)
• EPA Substance Registry System: (+)-(S)-benzoin Z-oxime(118353-47-2)

Safety Data

• Hazardous Substances Data: 118353-47-2(Hazardous Substances Data)

Upstream product

• 5928-67-6 (S)-(+)-benzoin 
• 118298-90-1 Trifluoro-acetic acid (S)-2-oxo-1,2-diphenyl-ethyl ester 
• 451-40-1 phenyl benzyl ketone 
• 5928-66-5 (R)-benzoin 
• 119-53-9 2-hydroxy-2-phenylacetophenone 
• 441-38-3 benzoin oxime 

Downstream Products

• 23364-44-5 (1S,2R)-2-Amino-1,2-diphenylethanol 
• 23190-16-1 (1R,2S)-2-Amino-1,2-diphenylethanol 

Relevant articles and documents

Readily available ruthenium complex for efficient dynamic kinetic resolution of aromatic α-hydroxy ketones

A ruthenium complex formed from commercially available [Ru(p-cymene)Cl 2]2 and 1,4-bis(diphenylphosphino)butane catalyzes the racemization of aromatic α-hydroxy ketones very efficiently at room temperature. The racemization is fully compatible with a kinetic resolution catalyzed by a lipase from Pseudomonas stutzeri. This is the first example of dynamic kinetic resolution of α-hydroxy ketones at ambient temperature in which the metal and enzyme catalysts work in concert in one pot at room temperature to give quantitative yields of esters of α-hydroxy ketones with very high enantioselectivity.

Lipase TL-mediated kinetic resolution of benzoin: Facile synthesis of (1R,2S)-erythro-2-amino-1,2-diphenylethanol

The lipase TL-mediated kinetic resolution of (±)-benzoin (1) proceeded to give the corresponding optically pure benzoin (R)-1. On the other hand, (S)-benzoin-O-acetate (5) could be hydrolyzed without epimerization to give (S)-benzoin (S)-1, under alkaline conditions. Further, (R)-1 was converted to (1R,2S)-2-amino-1,2-diphenylethanol (99:1 er) according to the procedure reported previously. (C) 2000 Elsevier Science Ltd.