118364-68-4

Basic information

• Product Name: 3',5'-bis-O-(t-butyldimethylsilyl)-N⁶-(4,4'-dimethoxytrityl)adenosine
• CAS NO: 118364-68-4
• Molecular Weight: 798.142
• Mol File: 118364-68-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3',5'-bis-O-(t-butyldimethylsilyl)-N⁶-(4,4'-dimethoxytrityl)adenosine(CAS DataBase Reference)
• NIST Chemistry Reference: 3',5'-bis-O-(t-butyldimethylsilyl)-N⁶-(4,4'-dimethoxytrityl)adenosine(118364-68-4)
• EPA Substance Registry System: 3',5'-bis-O-(t-butyldimethylsilyl)-N⁶-(4,4'-dimethoxytrityl)adenosine(118364-68-4)

Safety Data

• Hazardous Substances Data: 118364-68-4(Hazardous Substances Data)

Upstream product

• 58-61-7 adenosine 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 69504-03-6 3',5'-bis-O-(tert-butyldimethylsilyl)-β-D-adenosine 
• 40615-36-9 4,4'-dimethoxytrityl chloride 

Downstream Products

• 109923-56-0 N⁶0-(4,4'-dimethoxytrityl)-2'-O-tosyladenosine 

Relevant articles and documents

The Synthesis of C-Methyl Branched-Chain Deoxy Sugar Nucleosides by the Deoxygenative Methylation of O-Tosylated Adenosines with Grignard Reagents

The reaction of appropiately protected 2'-O-tosyladenosines with methylmagnesium bromide (or iodide) gave 9-(2-deoxy-3-C-methyl-β-D-threopentofuranosyl)adenine after deprotection.The same reaction on 3'-O-tosyladenosine derivatives afforded an epimeric pair of 2'-C-methyl-3'-deoxy sugar nucleosides.The modified structures of the sugar moieties were determined unambiguously.