1184-16-3 Usage
Description
BETA-NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE SODIUM SALT, also known as β-Nicotinamide Adenine Dinucleotide Phosphate (NADP+) and its reduced form (NADPH), is a coenzyme redox pair involved in a wide range of enzyme-catalyzed oxidation-reduction reactions. It plays a crucial role in various metabolic processes and acts as an electron acceptor used by cells. BETA-NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE SODIUM SALT is a white to slightly yellowish powder.
Uses
Used in Metabolic Processes:
BETA-NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE SODIUM SALT is used as a substrate in metabolic processes for its role in a variety of cellular functions.
Used in Enzyme-Catalyzed Oxidation-Reduction Reactions:
BETA-NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE SODIUM SALT is used as an electron acceptor in enzyme-catalyzed oxidation-reduction reactions, facilitating the transfer of electrons between molecules.
Used in Antioxidation Mechanisms:
BETA-NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE SODIUM SALT is used as a component of the NADP+/NADPH redox pair in various antioxidation mechanisms, which protect against the accumulation of reactive oxygen species.
Used in Research and Diagnostics:
BETA-NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE SODIUM SALT is used as a research tool for studying NADP and its role in cellular processes, as well as in diagnostic applications to assess enzyme activity and function.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, BETA-NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE SODIUM SALT is used as a key component in the development of drugs targeting metabolic disorders and oxidative stress-related conditions.
Used in Biotechnology:
BETA-NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE SODIUM SALT is employed in biotechnology applications, such as the enhancement of cellular metabolism and the study of redox reactions in genetically modified organisms.
Biochem/physiol Actions
Electron acceptor
Check Digit Verification of cas no
The CAS Registry Mumber 1184-16-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,1,8 and 4 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1184-16:
(6*1)+(5*1)+(4*8)+(3*4)+(2*1)+(1*6)=63
63 % 10 = 3
So 1184-16-3 is a valid CAS Registry Number.
1184-16-3Relevant articles and documents
Metaphosphate: A New Phosphoryl Donor for NAD Phosphorylation
Murata, Kousaku,Uchida, Tomofumi,Tani, Keiko,Kato, Jyoji,Chibata, Ichiro
, p. 61 - 68 (2007/10/02)
A new nicotinamid adenine dinucleotide (NAD) kinase which synthesizes nicotinamid adenine dinucleotide phosphate (NADP) from NAD and methaphosphate was found in some microorganisms.The activity of this enzyme, designated tentatively as methaphosphate-dependent NAD kinase, was detected in Acetobacter, Achromobacter, Brevibacterium, Corynebacterium and Micrococcus species, but was not detected in Escherichia, Proteus and Aerobacter species.The metaphosphate-dependent NAD kinase activity of Brevibacterium ammoniagenes IAM 1645 was not affected by culture conditions, though the adenosine-5'-triphosphate (ATP)-dependent NAD kinase activity was did.The metaphosphate-dependent NAD kinase activity from B. ammoniagenes also differed from the ATP-dependent NAD kinase activity in optimal pH of reaction and stability in heating and in freezing and thawing.Of phosphate polymers tested, the potent phosphoryl donor was metaphosphate alone, and other chain and ring phosphate polymers of different degrees of condensation were not utilized by this enzyme.