1184-89-0 Usage
Description
DIBROMOCHLORONITROMETHANE is a nitrogenous disinfection byproduct (N-DBP) that is found in drinking water. It is a compound with a chemical structure that includes two bromine atoms, one chlorine atom, and one nitro group attached to a central carbon atom. DIBROMOCHLORONITROMETHANE is known for its mutagenic properties and its ability to induce DNA strand breaks in mammalian cells.
Uses
Used in Environmental Chemistry and Water Treatment Industry:
DIBROMOCHLORONITROMETHANE is used as a compound of interest for understanding the formation and control of disinfection byproducts in drinking water. Its presence in water supplies can indicate the need for improved water treatment processes to ensure the safety and quality of drinking water.
Used in Research and Development:
DIBROMOCHLORONITROMETHANE serves as a model compound for studying the mutagenicity and genotoxicity of N-DBPs in various research applications. This helps scientists to better understand the potential health risks associated with exposure to these compounds and to develop strategies for mitigating their effects.
Used in Regulatory Compliance and Monitoring:
As a known N-DBP, DIBROMOCHLORONITROMETHANE is used as a reference compound in the development of regulatory standards and guidelines for drinking water quality. It is also utilized in monitoring programs to assess the effectiveness of water treatment processes in reducing the levels of N-DBPs in drinking water supplies.
Used in Public Health and Risk Assessment:
DIBROMOCHLORONITROMETHANE plays a role in public health initiatives by contributing to the understanding of the potential health risks associated with exposure to N-DBPs in drinking water. This knowledge is crucial for developing risk assessment models and informing policy decisions related to water safety and public health protection.
Check Digit Verification of cas no
The CAS Registry Mumber 1184-89-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,1,8 and 4 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1184-89:
(6*1)+(5*1)+(4*8)+(3*4)+(2*8)+(1*9)=80
80 % 10 = 0
So 1184-89-0 is a valid CAS Registry Number.
1184-89-0Relevant articles and documents
Halonitromethane Drinking Water Disinfection Byproducts: Chemical Characterization and Mammalian Cell Cytotoxicity and Genotoxicity
Plewa, Michael J.,Wagner, Elizabeth D.,Jazwierska, Paulina,Richardson, Susan D.,Chen, Paul H.,McKague, A. Bruce
, p. 62 - 68 (2004)
Halonitromethanes are drinking water disinfection byproducts that have recently received a high priority for health effects research from the U.S. Environmental Protection Agency (EPA). Our purpose was to identify and synthesize where necessary the mixed halonitromethanes and to determine the chronic cytotoxicity and the acute genotoxicity of these agents in mammalian cells. The halonitromethanes included bromonitromethane (BNM), dibromonitromethane (DBNM), tribromonitromethane (TBNM), bromochloronitromethane (BCNM), dibromochloronitromethane (DBCNM), bromodichloronitromethane (BDCNM), chloronitromethane (CNM), dichloronitromethane (DCNM), and trichloronitromethane (TCNM). Low- and high-resolution gas chromatography/mass spectrometry (GC/MS) was used to identify the mixed chloro-bromonitromethanes in finished drinking waters, and analytical standards that were not commercially available were synthesized (BDCNM, DBCNM, TBNM, CNM, DCNM, BCNM). The rank order of their chronic cytotoxicity (72 h exposure) to Chinese hamster ovary (CHO) cells was DBNM > DBCNM > BNM > TBNM > BDCNM > BCNM > DCNM > CNM > TCNM. The rank order to induce genomic DNA damage in CHO cells was DBNM > BDCNM > TBNM > TCNM > BNM > DBCNM > BCNM > DCNM > CNM. The brominated nitromethanes were more cytotoxic and genotoxic than their chlorinated analogues. This research demonstrated the integration of the procedures for the analytical chemistry and analytical biology when working with limited amounts of sample. The halonitromethanes are potent mammalian cell cytotoxins and genotoxins and may pose a hazard to the public health and the environment.